TUBB2B Antibody (N-term) #abs101264

abs101264-50ul

In Stock

228

Description

The affinity purified rabbit polyclonal antibody (Pab) is derived from peptides.

Other names

Tubulin beta-2B chain, TUBB2B；TUBB2B

Source

Rabbit

Specificity

The TUBB2B antibody is derived from rabbits that were immunized with a synthetic peptide conjugated to KLH. This peptide corresponds to amino acids 12-39 in the N-terminal region of the human TUBB2B protein. To create an alternative version of the content, I will generate a completely different text based on the original information.

Species Reactivity

Human

Predictive reaction species

C, Pr, M, R, B, X, P

Application

IF~~1:10~50
WB~~1:1000
IHC-P~~1:10~50

Properties

Clonality

Polyclonal Antibody

Isotype

Rabbit Ig

Stability & Storage

To ensure the quality of the product, it is recommended to keep it refrigerated at a temperature range of 2-8°C for a maximum of two weeks. For extended storage, it is best to freeze the product at a temperature of -20°C in smaller portions to prevent any freeze-thaw cycles that may cause deterioration.

Storage buffer

This antibody is purified through a peptide affinity purification method after passing through a protein A column. It is supplied in PBS containing 0.09% (w/v) sodium azide.

Research area

Signal Transduction

Research area

Background

Microtubules, which are composed primarily of tubulin, are essential to a wide range of cellular activities. In particular, tubulin binds to two molecules of GTP, with each chain having a different type of binding site. The beta chain has an exchangeable site, while the alpha chain has a non-exchangeable site. Researchers have found that TUBB2B plays an important role in the migration of neurons, highlighting the critical nature of this protein in the development and function of the nervous system.

Celluar localization

Cytoplasm, cytoskeleton.

UniPort

Q9BVA1

References

References

Xu, W., et al. Mol. Cancer Ther. 8(12):3318-3330(2009)
Jaglin, X.H., et al. Nat. Genet. 41(6):746-752(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Cucchiarelli, V., et al. Cell Motil. Cytoskeleton 65(8):675-685(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)