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Rabbit Anti-CCL16 Polyclonal Antibody#abs139432

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Description

Catalog-specification	Delivery time	USD price
abs139432-100ug	1-2 Weeks	301.0
abs139432-50ug	1-2 Weeks	201.0

Overview
catalog	abs139432
Other names	C-C motif chemokine 16, also known as CCL16 or CCL16_HUMAN, is a chemokine protein. It is also referred to as Chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4, HCC4, IL-10-inducible chemokine, IL10 inducible chemokine, ILINCK, LCC-1, LCC1, Liver CC chemokine 1 precursor, Liver expressed chemokine, Liver-expressed chemokine, LMC, Lymphocyte and monocyte chemoattractant, Monotactin 1, Monotactin-1, MTN-1, Mtn1, NCC-4, NCC4, New CC chemokine 4, SCYA16, SCYL4, Small inducible cytokine A16 precursor, Small inducible cytokine subfamily A (Cys Cys) member 16, and Small-inducible cytokine A16. This protein is involved in immune responses and functions as a chemotactic factor for lymphocytes and monocytes. It is produced by various cell types, including liver cells. C-C motif chemokine 16 plays a role in attracting immune cells to inflammatory sites and is believed to contribute to the recruitment of immune cells in certain diseases. In summary, C-C motif chemokine 16, also known as CCL16, is an important chemokine involved in immune responses and cell recruitment. It is produced by different cell types and plays a role in inflammation and immune cell migration.
Source	Rabbit
Specificity	The antibody against CCL16 is capable of detecting the full range of endogenous CCL16 levels. This means that it can effectively identify and measure the total amount of CCL16 present in a sample, providing valuable insights into the biological processes and pathways in which this protein is involved. By using this CCL16 antibody, researchers can gain a deeper understanding of the role that this cytokine plays in human physiology and disease, leading to new approaches for diagnosis and treatment.
Species Reactivity	Human
Antigen	CCL16
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CCL16.
MW	14 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	One year storage at -20 °C is recommended to maintain the quality of the product. It is important to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Tissue specificity	Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Celluar localization	Extracellular region or secreted;
UniPort	O15467