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Rabbit Anti-CCL17 Polyclonal Antibody#abs139433

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Description

Catalog-specification	Delivery time	USD price
abs139433-100ug	1-2 Weeks	301.0
abs139433-50ug	1-2 Weeks	201.0

Overview
catalog	abs139433
Other names	CC chemokine TARC, also known as small inducible cytokine A17, CCL17 or thymus and activation regulated chemokine, belongs to the small inducible cytokine subfamily A (Cys Cys) and plays a key role in cell migration and immune response. Its precursor is encoded by the A-152E5.3 or A152E53 gene, also known as SCYA17 or MGC138271/273. Commonly referred to as ABCD2 or ABCD 2, CC chemokine TARC is the chemokine CC motif ligand 17 and is involved in directing T cell migration. Its main function is attracting immune cells to inflamed tissues, where they can help fight infections and other disease-related conditions. In summary, CC chemokine TARC is a crucial chemokine involved in the immune response and is encoded by various genes with different names such as SCYA17, MGC138271/273, A-152E5.3, A152E53, ABCD2 and ABCD 2.
Source	Rabbit
Specificity	The CCL17 Antibody is capable of identifying the overall levels of endogenous CCL17. This information indicates that the antibody has the potential to detect the total amount of CCL17 present in a given sample. By rearranging the original text, this content emphasizes the key concept of the antibody's ability to detect CCL17 levels and reinforces the significance of this information.
Species Reactivity	Human
Predictive reaction species	Pig;Dog;
Antigen	CCL17
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CCL17.
MW	11 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography with SulfoLink™ Coupling Resin was utilized to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its quality, keep the product stored at a temperature of -20 °C for a period of one year. Make sure to avoid subjecting it to repeated freeze-thaw cycles as this can affect the product's efficacy over time.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
Tissue specificity	Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
Celluar localization	Extracellular region or secreted;
UniPort	Q92583