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Rabbit Anti-HRT2 Polyclonal Antibody#abs140446

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Description

Catalog-specification	Delivery time	USD price
abs140446-100ug	1-2 Weeks	301.0
abs140446-50ug	1-2 Weeks	201.0

Overview
catalog	abs140446
Other names	Protein gridlock homolog, also known as bHLHb32, Cardiovascular helix loop helix factor 1, or CHF1, plays a crucial role in cardiovascular development. It is a member of the Class B basic helix-loop-helix protein 32 family, also referred to as GRIDLOCK or GRL. Another name for this protein is Hairy and enhancer of split-related protein 2 or HES-related repressor protein 2. Hairy-related transcription factor 2, or hey2, is another designation for this protein. It is involved in regulating gene expression and is characterized by the presence of a YRPW motif. HES-related repressor protein 1, known as HERP1, is a closely related protein to HEY2. Please note that the generated content above is rearrangement-based and may not precisely capture the original text information.
Source	Rabbit
Specificity	The total level of endogenous HRT2 can be accurately identified using the HRT2 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	HRT2
Application	ELISA (peptide) is conducted at a dilution range of 1:20000 to 1:40000, while the dilution range for IF/ICC is 1:100 to 1:500. In Western blotting (WB), the recommended dilution is 1:1000. It is important to note that this rearranged content is based on the original information provided.
Immunogen	A synthesized peptide derived from human HRT2.
MW	36kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Celluar localization	Nucleus;
UniPort	Q9UBP5