Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-HJURP Polyclonal Antibody#abs138462

Description

Catalog-specification	Delivery time	USD price
abs138462-100ug	1-2 Weeks	301.0
abs138462-50ug	1-2 Weeks	201.0

Please note that the price provided is for reference only. For detailed pricing information, please get in touch with our seller Vecent. It is important to note that the content generated must be based on the original text information while ensuring that it is not generated in the same manner as ChapGPT. To make the communication process more effective, it is recommended to use a language model to generate text that is different from the original content.

Overview
catalog	abs138462
Other names	FAKTS, also known as 14-3-3-associated AKT substrate, is a protein encoded by the fetal liver-expressing gene 1 (FLEG1). FLEG1, also referred to as HJURP (Holliday junction recognition protein) or up-regulated in lung cancer 9 (URLC9), is expressed in fetal liver tissue. The hFLEG1 protein plays a crucial role in various biological processes and is associated with lung cancer. By rearranging and rephrasing the provided information, we can obtain a highly similar content while still conveying the same meaning.
Source	Rabbit
Specificity	The total HJURP levels in the body can be detected using the HJURP Antibody. By utilizing this antibody, researchers are able to accurately measure the endogenous levels of HJURP protein. It provides valuable insights into the presence and quantity of HJURP in various biological samples. This information assists in understanding the role of HJURP in cellular processes and its potential implications in different diseases and conditions. The HJURP Antibody is a useful tool for studying the function and regulation of HJURP in biological systems.
Species Reactivity	Human
Predictive reaction species	Horse
Antigen	HJURP
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human HJURP.
MW	84 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To obtain a highly pure and specific antiserum, this method was utilized to isolate the desired peptides for the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store at a temperature of -20 °C for a duration of one year. To maintain its quality, it is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	Store Rabbit IgG in phosphate buffered saline at a pH of 7.4. The solution should contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to store it at a temperature of -20 °C. This particular IgG is stable for a period of 12 months starting from the date of receipt.
Target
Background	Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Tissue specificity	According to PubMed:17256767, highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411, highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung.
Celluar localization	Cytosol;Mitochondrion;Nucleus;
UniPort	Q8NCD3