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Rabbit Anti-Histone 1F0 Polyclonal Antibody#abs133375

Please note that the price mentioned above is only for your reference. To obtain detailed pricing information, we kindly ask you to get in touch with our sales representative, Vecent. Western blot analysis of extracts from A549 cells, using Histone 1F0 antibody. This product is for research use...

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Description

Catalog-specification	Delivery time	USD price
abs133375-100ug	1-2 Weeks	301.0
abs133375-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. To obtain detailed pricing information, we kindly ask you to get in touch with our sales representative, Vecent.

Overview
catalog	abs133375
Other names	Histone H1(0), also known as H1 histone family member 0 or H10, is a protein that plays an essential role in the packaging of DNA in the nucleus. It is encoded by the H1F0 gene and is commonly referred to as H10_HUMAN or h1f0. Other names for this protein include H1FV and Histone H1'. One important characteristic of Histone H1(0) is its N-terminally processed structure, which distinguishes it from other histone H1 variants such as Histone H1.0 and Histone H10. It is also associated with the designation MGC5241. In summary, Histone H1(0), with its various names and designations, is a significant protein involved in DNA packaging and plays a vital role in maintaining the integrity of the genome. Its unique N-terminally processed structure sets it apart from other histone H1 variants.
Source	Rabbit
Specificity	Histone 1F0Histone 1F0。。
Species Reactivity	Human;Mouse;Rat
Antigen	Histone 1F0
Application	ELISA (peptide) can be conducted at dilutions ranging from 1:20000 to 1:40000. For WB, the recommended dilution is 1:500 to 1:1000, while for IF/ICC it is 1:100 to 1:500. It is essential to maintain the original text information while rearranging the content.
Immunogen	A synthesized peptide.
MW	20 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in the process of purifying the antiserum by means of peptide affinity chromatography. We were successful in obtaining a highly purified antiserum using this method.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the product in a freezer at a temperature of -20 °C for a duration of one year. It is best to avoid frequent thaw and freeze cycles to maintain its potency.
Storage buffer	Phosphate buffered saline with Rabbit IgG can be stored in -20 °C with stability up to 12 months from the date of receipt. The solution has a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol as key components. Ensure to handle the solution with care and store accordingly to maintain its composition.
Target
Background	Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Tissue specificity	Both the unedited and the RNA edited versions are induced by butyrate (at protein level). Only RNA edited version is induced by DTT, vinblastine or TNF (at protein level).
Posttranslational modification	Phosphorylated on Ser-17 in RNA edited version.ADP-ribosylated on Ser-104 in response to DNA damage.
Celluar localization	Cytoskeleton;Golgi apparatus;Nucleus;
UniPort	P07305