Rabbit Anti-hCG Beta Polyclonal Antibody #abs130114

abs130114-50ug

1-2 Weeks

201

abs130114-100ug

1-2 Weeks

301

Other names

hCGB; CG-beta; CG-beta; CGB; CGB3; CGB5; CGB7; CGB8; CGHB_HUMAN; Choriogonadotropin subunit beta; Chorionic gonadotrophin chain beta; Chorionic gonadotropin beta 3 subunit; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin beta subunit.
The given text contains various terms related to choriogonadotropin or chorionic gonadotropin (CG). CG is a hormone produced during pregnancy by the placenta. The hormone is essential for maintaining pregnancy and is commonly used in pregnancy tests and fertility treatments.
These terms include different versions of the CG-beta subunit, such as CG-beta, CGB3, CGB5, CGB7, and CGB8. They represent specific variations of the beta subunit of chorionic gonadotropin. The CG-beta subunit combines with the alpha subunit to form the complete hormone.
The CG-beta subunit is also referred to as hCGB (human choriogonadotropin beta) and is classified as CGHB_HUMAN. It plays a crucial role in pregnancy and is a key marker for detecting early pregnancy and monitoring certain pregnancy-related conditions.
In summary, the mentioned terms are all related to the beta subunit of chorionic gonadotropin, an important hormone in pregnancy.

Source

Rabbit

Specificity

The detection of endogenous levels of total hCG beta is accomplished by utilizing the hCG beta antibody. Through this method, the levels of hCG beta in the body can be accurately measured. By rearranging the content, we can state that the hCG beta antibody is employed to detect the total levels of endogenous hCG beta, enabling the precise assessment of its presence in the body.

Species Reactivity

Human;Mouse;Rat

Application

For Western blot, dilution ranges from 1:500 to 1:3000. Dilute for immunohistochemistry is from 1:50 to 1:200, and for IF/ICC is from 1:100 to 1:500. Additionally, dilution for ELISA (peptide) varies from 1:20000 to 1:40000. The above information can be rearranged to create a similar content with different wording.

Immunogen

A synthesized peptide derived from human hCG beta.

Properties

Concentration

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. The resulting product is highly purified and effective in its ability to neutralize specific antigens. The SulfoLink™ Coupling Resin provides excellent binding specificity and high affinity for the peptides, ensuring that only the desired antibodies are isolated and purified. The final purified antiserum can be used in a variety of clinical and experimental settings for diagnostic and therapeutic purposes.

Clonality

Polyclonal Antibody

Stability & Storage

To preserve the quality of the product, it is recommended to keep it stored at a temperature of -20 °C for a year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing. Proper storage measures will help maintain the integrity and effectiveness of the product.

Storage buffer

The rabbit IgG is stored in a solution of phosphate buffered saline at a pH of 7.4, with a concentration of 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. The stability of the IgG is guaranteed for a period of 12 months from the date of receipt.

Target

Background

The beta subunit of human chorionic gonadotropin (hCG) is a crucial component of this complex glycoprotein that is composed of two subunits, alpha and beta, which are non-covalently associated. The alpha subunit is identical to that found in pituitary gonadotropin hormones, such as LH, FSH, and TSH, while the beta subunits in each hormone are unique and confer receptor and biological specificity.
During pregnancy, the beta subunit of hCG is essential for maternal adaptation and plays an important role in stimulating the ovaries to produce the necessary steroids for maintaining the pregnancy. As a result, any abnormalities in hCG levels can lead to reproductive disorders or complications during pregnancy.
Understanding the functions and importance of the beta subunit of hCG is crucial to ensuring healthy pregnancies and preventing reproductive disorders.

Tissue specificity

Throughout pregnancy, there is a consistently high level of expression observed in the placenta.

Celluar localization

Extracellular region or secreted;

UniPort

P0DN86