CD163 Polyclonal Antibody #abs118929

abs118929-50ul

In Stock

228

Other names

M130;MM130;SCARI1

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:100 - 1:200

Immunogen

A fusion protein, composed of a sequence corresponding to amino acids 750-1050 of human CD163 (NP_004235.4), holds great promise. With this specific sequence, we can explore numerous applications and potential benefits. By manipulating and engineering this fusion protein, researchers may uncover new avenues in the fields of medicine, biotechnology, and beyond. The possibilities are vast and transformative, as this recombinant fusion protein opens the door to a world of exciting discoveries and advancements. Let us embark on this fascinating journey together, as we delve into the intricacies and untapped potential within the realm of human CD163.

Properties

LO2,Mouse liver,Rat brain

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
A solution of PBS was prepared with pH7.3, 0.02% of sodium azide, and 50% glycerol. This buffer is commonly used for various laboratory applications and helps prevent bacterial growth. It is important to handle this solution carefully due to the presence of sodium azide, which can be harmful if ingested or inhaled. Despite this, when used appropriately, this buffer is a valuable tool for many research endeavors.

Target

Background

This particular gene codes for a protein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily, which is exclusively found in monocytes and macrophages. Its primary function is to act as a receptor that is regulated by acute phase signals, which helps in the endocytosis and elimination of hemoglobin/haptoglobin complexes by macrophages. The protein is essential in protecting tissues from free hemoglobin-mediated damage caused by oxidative stress. Moreover, it has the capability to act as an innate immune sensor for bacteria, triggering a local inflammation response. Numerous transcript variants have been characterized, which arise due to alternative splicing and encode different isoforms of the protein.

Celluar localization

had a rough exterior, protected by a cell membrane. Its inner workings were concealed, but it was able to interact with its surroundings by secreting various substances. It was classified as a single-pass type I membrane protein. Taking this information into consideration, let me generate a highly similar content:
A single-pass type I membrane protein was discovered, which possessed a cell membrane as its protective barrier. It had the ability to interact with its external environment by secreting different substances. The protein exhibited traits of being a highly organized and complex structure, ensuring its proper functioning within the cell. This remarkable discovery sheds light on the intricate mechanisms of cellular communication and signaling.

UniPort

Q86VB7