ATP1B2 Polyclonal Antibody #abs118718

abs118718-50ul

In Stock

228

Other names

AMOG

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:200 - 1:500

Immunogen

In order to produce a recombinant fusion protein, we need to use a sequence that corresponds to amino acids 68-290 of the human ATP1B2 protein (NP_001669.3). This fusion protein will contain this specific sequence, which is important for its function and structure. By rearranging the information, we can ensure that the generated content is similar to the original text.

Properties

HepG2,H460,SH-SY5Y

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
The buffer used in this experiment was composed of PBS with a pH7.3, along with 50% glycerol and 0.02% of sodium azide. The solution was also supplemented with sodium azide, a common biological preservative, and glycerol to maintain the stability of the buffer. Overall, this buffer was prepared to help maintain the integrity of the experimental system throughout the study.

Target

Background

This gene encodes a protein that belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins. Specifically, it belongs to the subfamily of Na+/K+ -ATPases. The primary function of the Na+/K+ -ATPase is to establish and maintain the electrochemical gradients of sodium and potassium ions across the plasma membrane. These gradients are essential for various cellular processes, including osmoregulation, the transport of organic and inorganic molecules, and the electrical excitability of nerve and muscle cells. This enzyme is composed of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta).
The beta subunit controls the number of sodium pumps transported to the plasma membrane through the assembly of alpha/beta heterodimers. The glycoprotein subunit of the Na+/K+ -ATPase is encoded by multiple genes, and this gene specifically encodes a beta 2 subunit. Two transcript variants have been identified for this gene, and they encode different isoforms of the protein. Overall, this gene's protein product plays a crucial role in maintaining cellular homeostasis and enabling various physiological processes.

Celluar localization

Cell membrane,Single-pass type II membrane protein

UniPort

P14415