ATP1B1 Polyclonal Antibody #abs118890

abs118890-50ul

In Stock

228

Other names

ATP1B

Source

Rabbit

Species Reactivity

Human;Mouse

Application

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Immunogen

A fusion protein with a sequence that corresponds to amino acids 63-303 of the human ATP1B1 (NP_001668.1) has been developed. To create highly similar content, the text can be rephrased to say that a recombinant protein has been created that contains the specific amino acid sequence 63-303 of the human ATP1B1 protein. This fusion protein was engineered using modern genetic engineering techniques. The amino acid sequence of the recombinant protein is almost identical to that of the original ATP1B1 protein. This protein is anticipated to have a significant impact on the field of molecular biology, particularly regarding cellular transport mechanisms.

Properties

HepG2,A-549,U-251MG

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
，：pH7.30.02%50%，PBS。

Target

Background

This gene encodes a protein that is part of the Na+/K+ and H+/K+ ATPases beta chain family. It also belongs to the Na+/K+ -ATPases subfamily. The Na+/K+ -ATPase protein plays a crucial role in maintaining the electrochemical gradients of sodium and potassium ions across the cell membrane. These gradients are important for osmoregulation, the transportation of various molecules, and the electrical excitability of nerves and muscles. The enzyme consists of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit is responsible for regulating the number of sodium pumps transported to the cell membrane by forming alpha/beta heterodimers. Multiple genes encode the glycoprotein subunit of Na+/K+ -ATPase, with this gene specifically encoding the beta 1 subunit. Alternative splicing of the transcript variants results in different isoforms, although their biological significance is currently unknown.

Celluar localization

Cell membrane,Single-pass type II membrane protein

UniPort

P05026