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Rabbit Anti-GPR78 Polyclonal Antibody#abs133142

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Description

Catalog-specification	Delivery time	USD price
abs133142-100ug	1-2 Weeks	301.0
abs133142-50ug	1-2 Weeks	201.0

Overview
catalog	abs133142
Description	This receptor is known as an orphan receptor and exhibits notable levels of constitutive activity. Its function involves the stimulation of adenylate cyclase through G(s)-alpha protein, leading to an increase in intracellular cAMP levels.
Other names	The FLJ98800 protein is a G protein coupled receptor known as GPR78 or G-protein coupled receptor 78. This receptor plays a crucial role in signal transduction and is expressed in various organs and tissues throughout the body. The GPR78 protein is encoded by the PRO19818 gene, and its function is still being extensively studied. Interestingly, this protein has also been referred to as UNQ5925 in some studies. Overall, the role of GPR78 in human physiology and disease states will be an exciting area of research for many years to come.
Source	Rabbit
Specificity	The detection of total GPR78 at its endogenous levels can be achieved using the GPR78 antibody.
Species Reactivity	Human;Mouse
Antigen	GPR78
Application	The dilution ratios for Western Blotting (WB) range from 1:500 to 1:2000, for Immunohistochemistry (IHC) range from 1:50 to 1:200, and for ELISA (peptide) range from 1:20000 to 1:40000. These dilution ranges are commonly used in the laboratory to achieve optimal results for each technique.
Immunogen	A synthesized peptide.
MW	39 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to perform peptide affinity chromatography in order to purify the antiserum. Let me generate a highly similar content by rearranging the above information while ensuring it remains based on the original text: The purification of the antiserum involved the utilization of SulfoLink™ Coupling Resin through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Please make sure to avoid repeated freeze/thaw cycles and store the product at -20 °C for a year.
Storage buffer	The solution contains Rabbit IgG, which is dissolved in phosphate buffered saline at pH 7.4. Additionally, the solution contains 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
Tissue specificity	High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney.
Celluar localization	Plasma Membrane;
UniPort	Q96P69