Rabbit Anti-sod2 Polyclonal Antibody#abs131223

abs131223-50ug

1-2 Weeks

201

abs131223-100ug

1-2 Weeks

301

Description

An antibody that targets Mn superoxide dismutase, also known as Mn SOD, as well as MVCD6 and SOD 2, is referred to as an Mn SOD antibody or SOD2 antibody. This particular antibody is used to detect the presence of Mn SOD in various biological samples, including human tissues. Mn SOD is an enzyme that plays a protective role against the harmful effects of oxygen radicals within cells. As such, the detection of Mn SOD is important in understanding cellular processes and disease states. The SODM_HUMAN antibody is another name used to refer to the Mn SOD antibody.

Other names

IPO B, also known as indophenoloxidase B, is an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative stress. Another name for this enzyme is manganese-containing superoxide dismutase, or MnSOD for short. MnSOD is found in the mitochondria of cells, where it helps convert harmful superoxide radicals into less harmful hydrogen peroxide and oxygen.
In humans, MnSOD is encoded by the SOD2 gene, which is located on chromosome 6. Mutations in this gene have been linked to a variety of diseases, including cancer, Parkinson's disease, and Alzheimer's disease.
Despite its importance, MnSOD is not always able to keep up with the high levels of oxidative stress that can occur in cells. This is why antioxidant supplements, such as vitamin C and vitamin E, are often recommended to help support the body's natural defenses against free radicals and other harmful compounds.
In conclusion, MnSOD is a vital enzyme that helps protect cells from oxidative damage. By understanding its role in the body, we can take steps to support its function and improve our overall health and well-being.

Source

Rabbit

Specificity

The sod2 Antibody is specifically designed to identify and quantify the levels of endogenous total sod2 protein in a sample. By recognizing and binding to the sod2 protein, the antibody enables researchers to measure the amount of sod2 present in biological samples. This detection method allows for the assessment of sod2 levels and helps to understand its role in various cellular processes. Reordering the content: The sod2 Antibody is an essential tool for detecting the levels of total sod2 protein in a sample. It specifically recognizes the endogenous sod2 protein and aids in quantifying its abundance. This antibody-based detection approach is crucial for determining the amount of sod2 present in biological samples, contributing to the understanding of its biological significance and function in different cellular processes.

Predictive reaction species

Xenopus;Zebrafish;Pig;Sheep;Horse;Bovine;Rabbit

Application

The recommended dilution for Western blot is 1:500-1:2000, while for ELISA using the peptide, it is 1:20000-1:40000. It is important to adhere to these dilution guidelines to ensure accurate and reliable results in your experiments. By following the recommended dilution range, you can optimize your assay conditions and generate the most precise data possible. Don't forget to use appropriate controls and replicate samples to ensure the validity of your results.

A synthesized peptide derived from human sod2.

Properties

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, we successfully purified the antiserum through the process of peptide affinity chromatography. This allowed for a highly effective and efficient purification method, resulting in a high-quality final product.

Clonality

Polyclonal Antibody

To maintain the quality of the product, it is advised to store it at a temperature of -20 °C for a period of one year. It is recommended to avoid repeated freeze and thaw cycles to prevent any possible damage or deterioration. Thus, ensuring proper storage conditions can help in preserving the product's effectiveness and usefulness for an extended period.

Storage buffer

The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the Rabbit IgG is guaranteed for a period of 12 months from the date of receipt.

Target

Background

The cells produce superoxide anion radicals, which are toxic to biological systems. However, a substance called destroys these radicals, protecting the cells from their harmful effects.

Tissue specificity

Expression is regulated by KRIT1.

Celluar localization

Extracellular region or secreted;Mitochondrion;

P04179