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Rabbit Anti-RBL2 Polyclonal Antibody#abs137271

Please note that the provided price is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent. Western blot analysis RBL2 using MCF7 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs137271-100ug	1-2 Weeks	301.0
abs137271-50ug	1-2 Weeks	201.0

Please note that the provided price is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent.

Overview
catalog	abs137271
Other names	130; 130; IB4; p130; PPAR-alpha128; PRB2; Rb2; Rbl2; RBL2_HUMAN; RBR 2; RBR-2; RBR2; 2; 2; 2; RIC128。，。
Source	Rabbit
Specificity	The RBL2 Antibody is designed to identify total RBL2 at natural levels within the body. The antibody aims to recognize any endogenous RBL2 present and can be used to detect the protein in a variety of settings.
Species Reactivity	Human;Rat
Antigen	RBL2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RBL2.
MW	128kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to note that the product should not be subject to repeated freeze/thaw cycles, as this may affect its efficacy. Taking these simple precautions can help ensure that the product remains stable and reliable for its intended use.
Storage buffer	This Rabbit IgG is stored in phosphate buffered saline at a pH of 7.4 with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and can remain stable for up to 12 months from the date of receipt.
Target
Background	Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
Tissue specificity	G0-restricted expression.
Posttranslational modification	During G0 and early G1 phase of the cell cycle, phosphorylated on Ser-639 and on 5 sites within the domain B. Phosphorylation on Ser-672 in G1 leads to its ubiquitin-dependent proteolysis.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	Q08999