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Rabbit Anti-GNRHR Polyclonal Antibody#abs137905

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Description

Catalog-specification	Delivery time	USD price
abs137905-100ug	1-2 Weeks	301.0
abs137905-50ug	1-2 Weeks	201.0

Overview
catalog	abs137905
Other names	The GnRH receptor, also known as GnRH-R or GNRHR, is a vital factor in hormone signaling. It is encoded by the GNRHR_HUMAN gene and also referred to as GNRHR1 or GRHR. This receptor plays a crucial role in the regulation of the reproductive system by binding to gonadotropin-releasing hormone (GnRH). Its alternative names such as HH7, lh-rh, LHRHR, LRHR, and luliberin receptor highlight its association with luteinizing-releasing hormone and luteinizing hormone releasing hormone receptor. Overall, the GnRH receptor, classified as type I, plays a pivotal role in reproductive processes.
Source	Rabbit
Specificity	The GNRHR Antibody is designed to identify the total GNRHR levels within the body. It can accurately detect the endogenous levels of this protein and is a reliable tool for researchers in various fields. By using this antibody, scientists can gain insights into the function and regulation of the GNRHR protein. Overall, the GNRHR Antibody is a valuable asset for scientific research and can facilitate the development of new therapies and treatments.
Species Reactivity	Human
Predictive reaction species	Rabbit;Dog;
Antigen	GNRHR
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GNRHR.
MW	38 kDa.
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification process of the antiserum involved peptide affinity chromatography. A highly similar content can be created based on this information by rearranging the sentence structures and maintaining the original meaning. For example: Peptide affinity chromatography was utilized alongside SulfoLink™ Coupling Resin to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the store at a temperature of -20 °C for a year. It is important to avoid subjecting the store to repeated freeze/thaw cycles.
Storage buffer	This is rabbit IgG in phosphate buffered saline with a pH level of 7.4, 150mM NaCl, 0.02% of sodium azide, and 50% glycerol. It is advised to store it at -20°C and it remains stable for up to 12 months from the date of receipt.
Target
Background	Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Tissue specificity	Pituitary, ovary, testis, breast and prostate but not in liver and spleen.
Celluar localization	Plasma Membrane;
UniPort	P30968