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Rabbit Anti-FXYD2 Polyclonal Antibody#abs139461

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Description

Catalog-specification	Delivery time	USD price
abs139461-100ug	1-2 Weeks	301.0
abs139461-50ug	1-2 Weeks	201.0

Overview
catalog	abs139461
Other names	The sodium potassium ATPase, gamma-1 polypeptide, also known as ATP 1C, is a critical component of the sodium potassium pump. The ATP1 G1 gene encodes the protein responsible for maintaining the electrochemical gradients in cells by transporting sodium and potassium ions across cell membranes. The protein is also known as ATP1C or ATP1G 1 and is part of the FXYD family of proteins that regulate ion transport. The Gamma subunit of sodium potassium ATPase plays a vital role in the proper functioning of the pump. Mutations in ATP1G1 are responsible for hypomagnesemia 2, renal, a rare kidney disease that affects the regulation of magnesium levels in the body. The sodium/potassium-transporting ATPase gamma chain is crucial for a wide range of biological processes and is found in all cells.
Source	Rabbit
Specificity	The detection of total FXYD2 is enabled by the FXYD2 Antibody, which specifically targets the endogenous levels of this protein. To reiterate, this antibody is capable of identifying the overall amount of FXYD2 present in a sample. When utilized, it effectively recognizes and binds to this protein, allowing for its measurement and analysis.
Species Reactivity	Human
Antigen	FXYD2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human FXYD2.
MW	7 kDa
Properties
Concentration	1mg/ml
purification	To purify the antiserum, the SulfoLink™ Coupling Resin was employed in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is crucial to prevent the product from undergoing repeated freeze/thaw cycles.
Storage buffer	The Rabbit IgG can be stored in a solution of phosphate buffered saline at pH 7.4, which contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To ensure its shelf life, it should be kept at a temperature of -20°C and can remain stable for 12 months since it was received.
Target
Background	May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
Tissue specificity	Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P54710