Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-EPO Polyclonal Antibody#abs131280

Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Western blot analysis of EPO expression in HepG2 cells This product is for research use only, not for use in diagnostic prodecures or in human.

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs131280-100ug	1-2 Weeks	301.0
abs131280-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent.

Overview
catalog	abs131280
Description	Diabetes mellitus can lead to various pathological conditions affecting multiple tissues and organs. These conditions encompass diabetic retinopathy, diabetic nephropathy resulting in end-stage renal disease, and diabetic neuropathy. Among diabetic adults, diabetic retinopathy remains the primary cause of new-onset blindness. It is characterized by increased tissue ischemia and angiogenesis alongside vascular permeability.
Other names	Erythropoietin (EPO), also known as Epoetin, is a therapeutic protein that stimulates the production of red blood cells. It is derived from the Erythropoietin precursor and has been commonly used in medicine. Another variant, EPO alpha, is also available as a drug. Additionally, there is a specific variant called MVCD2. These substances all serve the purpose of regulating and increasing red blood cell production in the body.
Source	Rabbit
Specificity	The EPO Antibody is capable of detecting the overall levels of endogenous EPO.
Species Reactivity	Human;Mouse;Rat
Antigen	EPO
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human EPO.
MW	21 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography. This process allowed for the removal of impurities and isolation of the desired antibodies for further use.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid any instances of repeated freeze/thaw cycles, as this can have a negative impact on the product's integrity. By taking these precautions, you can ensure that the product remains in optimal condition for its intended use.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Tissue specificity	Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Celluar localization	Extracellular region or secreted;
UniPort	P01588