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Rabbit Anti-ELOA3 Polyclonal Antibody#abs140693

Description

Catalog-specification	Delivery time	USD price
abs140693-100ug	1-2 Weeks	301.0
abs140693-50ug	1-2 Weeks	201.0

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Overview
catalog	abs140693
Other names	Elongin A3, also known as EloA3 or HsT829, is a protein involved in transcription regulation. It is a subunit of the RNA polymerase II transcription factor SIII. Another name for this protein is TCEB3L2 or transcription elongation factor B polypeptide 3C (elongin A3). This protein plays a crucial role in the elongation phase of transcription. Its function is to facilitate the movement of RNA polymerase II along the DNA template, allowing efficient transcription of genes. Understanding the role of EloA3 in transcription regulation is important for unraveling the complex mechanisms governing gene expression.
Source	Rabbit
Specificity	The total ELOA3 levels can be detected by using the ELOA3 Antibody, which can accurately recognize the endogenous levels of this protein. To create a similar content based on this information, one can rearrange the wording and convey the same message.
Species Reactivity	Human
Antigen	ELOA3
Application	For western blot analysis, a dilution ratio of 1:500 to 1:1000 is recommended. For immunofluorescence and immunocytochemistry experiments, a dilution ratio of 1:100 to 1:500 is recommended. When performing ELISA using peptide, it is suggested to use a dilution ratio of 1:20000 to 1:40000. It is important to follow these dilution ratios to obtain accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	60 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles to maintain its quality and integrity.
Storage buffer	This product is Rabbit IgG, which is stored in a freezing temperature of -20°C. It contains phosphate buffered saline at a pH of 7.4, along with 150mM NaCl, 0.02% sodium azide, and 50% glycerol, making it highly stable for up to 12 months from the date of receipt.
Target
Background	SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Tissue specificity	Widely expressed.
Celluar localization	Nucleus;
UniPort	Q8NG57