Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-Vav2 Polyclonal Antibody#abs140582

Please note that the mentioned price is only for your reference. Kindly contact our seller, Vecent, for the detailed price. Western blot analysis Vav2 using NIH-3T3 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs140582-100ug	1-2 Weeks	301.0
abs140582-50ug	1-2 Weeks	201.0

Please note that the mentioned price is only for your reference. Kindly contact our seller, Vecent, for the detailed price.

Overview
catalog	abs140582
Other names	VAV2 is a guanine nucleotide exchange factor and an oncogene. It is also referred to as vav 2 protein or VAV 2 oncogene. The gene name is VAV-2, and it is associated with cancer development. VAV2 is an important protein involved in cellular signaling pathways. Its role as an oncogene suggests its potential involvement in tumorigenesis. The human VAV2 gene is identified by the symbol VAV2_HUMAN.
Source	Rabbit
Specificity	The detection of endogenous levels of total Vav2 is possible using the Vav2 antibody. The antibody ensures high specificity and sensitivity in detecting the Vav2 protein in samples. By targeting this protein, researchers can gain important insights into various cellular processes, including cell proliferation and differentiation. The Vav2 antibody is an important tool in the study of Vav2 and its role in different diseases, including cancer.
Species Reactivity	Human
Antigen	Vav2
Application	You can dilute the WB 1:1000, or use IF/ICC at a dilution of 1:100-1:500 for detection. A peptide ELISA can also be performed at a dilution range of 1:20000-1:40000 for quantitative analysis. To ensure optimum results, it is important to follow the recommended dilutions and protocols.
Immunogen	A synthesized peptide derived from human Vav2.
MW	101kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in purifying the antiserum. This process resulted in a highly purified antiserum that is similar to the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality and potency of this product, it is advised to store it at a temperature of -20°C for a period of one year. It is recommended to avoid subjecting it to any form of repeated freeze and thaw cycles to prevent any possible damage or loss of functionality.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline, with a pH of 7.4 and 150mM NaCl. It is also formulated with 0.02% sodium azide and 50% glycerol to enhance its stability. Recommended storage for this product is at -20°C. It is advisable to follow storage instructions to maintain the quality of product, as it can remain stable for up to 12 months from the date of receipt.
Target
Background	This protein is a guanine nucleotide exchange factor that specifically interacts with the Rho family of Ras-related GTPases. It plays a crucial role in the process of angiogenesis, which involves the growth and formation of new blood vessels. The recruitment of this protein by phosphorylated EPHA2 is essential for the activation of the RAC1 GTPase, which in turn promotes vascular endothelial cell migration and assembly. These findings suggest that this protein could be a potential therapeutic target for the treatment of angiogenesis-related diseases.
Tissue specificity	Widely expressed.
Posttranslational modification	Phosphorylated on tyrosine residues in response to FGR activation.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	P52735