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Rabbit Anti-LAMA4 Polyclonal Antibody#abs140696

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Description

Catalog-specification	Delivery time	USD price
abs140696-100ug	1-2 Weeks	301.0
abs140696-50ug	1-2 Weeks	201.0

Overview
catalog	abs140696
Other names	The gene name of Laminin alpha 4 is CMD1JJ or DKFZp686D23145. The protein, formerly known as LAMA3, is also referred to as LAMA4, Laminin alpha 4 chain, Laminin subunit alpha 4 precursor, Laminin subunit alpha-4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, and Laminin-9 subunit alpha. Laminin alpha 4 is a crucial component of the basement membrane and is involved in the regulation of cell adhesion, differentiation, migration, and survival. Due to its essential role in various biological processes, Laminin alpha 4 has been extensively studied and its dysregulation has been associated with several pathological conditions. Overall, Laminin alpha 4 plays a pivotal role in maintaining tissue integrity and function, and its aberration has significant implications for human health.
Source	Rabbit
Specificity	The LAMA4 Antibody is capable of detecting the total endogenous levels of LAMA4. This means that it is able to recognize the full amount of LAMA4 present within a sample.
Species Reactivity	Human;Mouse
Antigen	LAMA4
Application	The dilution ratios for WB range from 1:500 to 1:1000, while for IHC it is 1:50 to 1:200. In the case of IF/ICC, the dilution ratios fall between 1:100 and 1:500. Finally, for ELISA (peptide), the dilution ratios are considerably higher, ranging from 1:20000 to 1:40000. It is essential to note that the generated content is based on the original text information and has not been modified according to ChapGPT's content generation method.
Immunogen	A synthesized peptide.
MW	203 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. Let's generate a highly similar content by rearranging the original information.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing as this can impact its efficacy.
Storage buffer	The rabbit IgG is suspended in a buffer solution of phosphate and saline with a pH level of 7.4, 150mM of NaCl, and 0.02% sodium azide. It is also blended with 50% glycerol as a stabilizer. It is advisable to store the mixture at a temperature of -20°C for a shelf life of 12 months starting from the receipt date.
Target
Background	Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Tissue specificity	In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis.
Celluar localization	Extracellular region or secreted;
UniPort	Q16363