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Rabbit Anti-CGREF1 Polyclonal Antibody#abs140991

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Description

Catalog-specification	Delivery time	USD price
abs140991-100ug	1-2 Weeks	301.0
abs140991-50ug	1-2 Weeks	201.0

Overview
catalog	abs140991
Other names	One possible rearrangement of the given content: Cell growth can be regulated by EF hand domain-containing proteins, including CGR11 (also known as CGREF1 or Hydrophobestin). These regulators play important roles in controlling cell growth and division, and their dysregulation has been linked to various diseases such as cancer. CGR11, in particular, has been shown to modulate the expression of genes involved in cell cycle progression and apoptosis. Therefore, targeting CGR11 and related proteins may have therapeutic potential in cancer treatment.
Source	Rabbit
Specificity	The endogenous levels of total CGREF1 can be detected using the CGREF1 Antibody.
Species Reactivity	Human;Rat
Antigen	CGREF1
Application	The recommended dilution ranges for WB (Western Blot) are 1:500 to 1:1000, for IHC (Immunohistochemistry) are 1:50 to 1:200, for IF/ICC (Immunofluorescence/Immunocytochemistry) are 1:100 to 1:500, and for ELISA (Enzyme-Linked Immunosorbent Assay) with peptide detection are 1:20000 to 1:40000. It is essential to follow these dilution guidelines to achieve optimal results in the respective experimental techniques.
Immunogen	A synthesized peptide.
MW	31 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To ensure high quality, the process was carried out with great care and attention to detail. The end result was a purified antiserum that was highly effective and suitable for its intended purpose.
Clonality	Polyclonal Antibody
Stability & Storage	For optimal storage conditions, it is recommended to keep the item in a freezer at a temperature of -20 °C for up to a year. To prevent damage to the item, it is best to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be kept in phosphate buffered saline at a pH of 7.4 with a concentration of 150mM NaCl, accompanied by 0.02% sodium azide and 50% glycerol. It is important to store it at a temperature of -20 °C. It is also worth noting that this product remains stable for a period of 12 months starting from the date of its receipt.
Target
Background	Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines.
Tissue specificity	By p53/TP53.
Posttranslational modification	Probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides.
Celluar localization	Extracellular region or secreted;
UniPort	Q99674