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Rabbit Anti-KIR3.4 Polyclonal Antibody#abs140456

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Description

Catalog-specification	Delivery time	USD price
abs140456-100ug	1-2 Weeks	301.0
abs140456-50ug	1-2 Weeks	201.0

Overview
catalog	abs140456
Other names	There are several names for the cardiac ATP-sensitive potassium channel, including the potassium inwardly rectifying channel J5 and the potassium voltage-gated channel subfamily J member 5. Another name for this channel is the GIRK-4 or G protein-activated inward rectifier potassium channel 4. The heart KATP channel and inward rectifier K(+) channel Kir3.4 are also names for this channel. Similarly, the inward rectifier potassium channel KIR3.4 and the potassium inwardly rectifying channel subfamily J member 5 are alternative names. The IRK-4 and LQT13 are also names for the cardiac inward rectifier. Lastly, the Kcnj5 or KCNJ5 and KATP-1 or KATP1 are other names for this channel. Regardless of the name, these channels play an important role in regulating the heartbeat and maintaining proper heart function.
Source	Rabbit
Specificity	The KIR3.4 Antibody is capable of identifying the total levels of endogenous KIR3.4 protein. The content can be rephrased keeping the original text information intact.
Species Reactivity	Human
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	KIR3.4
Application	1:1000，/1:100-1:500，ELISA（）1:20000-1:40000。，。
Immunogen	A synthesized peptide derived from human KIR3.4.
MW	48kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography for purification. You can rest assured that the generated content is based on the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Tissue specificity	Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa.
Celluar localization	Plasma Membrane;
UniPort	P48544