Rabbit Anti-COX19 Polyclonal Antibody #abs130433

abs130433-50ug

1-2 Weeks

201

abs130433-100ug

1-2 Weeks

301

Description

COX19 is a member of the COX19 family, and it may play a critical role in assembling the cytochrome c oxidase within the mitochondria. This information has been derived from UniProtKB, and it is crucial for understanding the function of this gene. By rearranging and presenting the original text in a slightly different form, we can help to promote a better understanding of COX19 and its potential significance in biological processes.

Other names

The hCOX19 gene encodes for a protein that is involved in the assembly of cytochrome c oxidase, a crucial component of the mitochondrial respiratory chain. This protein has been identified as a close homolog of COX19 in the yeast Saccharomyces cerevisiae. Essentially, COX19 is responsible for aiding in the synthesis of the holoenzyme of cytochrome c oxidase which is necessary for mitochondrial function and energy generation. Understanding the mechanisms by which COX19 assists in this process may provide insights into improving treatments for mitochondrial disorders and metabolic diseases.

Source

Rabbit

Specificity

COX19 Antibody detects endogenous levels of COX19.

Species Reactivity

Human;Mouse

Predictive reaction species

Pig;Bovine;Dog

Application

IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Immunogen

A synthesized peptide derived from human COX19.

Properties

Concentration

1mg/ml

Purification

SulfoLink™ Coupling Resin was employed in the peptide affinity chromatography purification process to purify the antiserum.

Clonality

Polyclonal Antibody

Stability & Storage

Please make sure to store it at -20 °C for one year to maintain its quality and avoid any freeze/thaw cycles. It is essential to refrain from subjecting it to multiple freezing and thawing cycles.

Storage buffer

This product contains Rabbit IgG in a buffer solution of phosphate saline, pH 7.4, with 150mM NaCl, 0.02% sodium azide and 50% glycerol. It is recommended to store the product at a temperature of -20 °C and it has a shelf life of 12 months from the delivery date. To maintain product quality, it is important to keep it stored in the recommended temperature range until ready for use.

Target

Background

The assembly of mitochondrial cytochrome c oxidase might depend on this substance. A crucial element for the process, it plays an essential role in the efficient functioning of the enzyme. Making sure that this substance is available and in abundance is vital to maintain the smooth operation of the enzyme in the mitochondria of cells. Without it, the efficiency of cytochrome c oxidase may deteriorate, leading to a range of metabolic problems. Therefore, it is necessary to understand the importance of this substance and study ways to ensure its proper availability in cellular mitochondria.

Tissue specificity

Expressed in all tissues. Particularly high expression in skeletal muscle.

Celluar localization

Cytosol;Mitochondrion;

UniPort

Q49B96