Rabbit Anti-SFXN4 Polyclonal Antibody #abs130435

abs130435-50ug

1-2 Weeks

201

abs130435-100ug

1-2 Weeks

301

Description

Sfxn4 is a member of the sideroflexin family and has the potential to transport iron. It is noteworthy that 3 isoforms of this protein are produced in humans via alternative splicing. This information has been extracted from UniProtKB and has been rearranged to generate a highly similar version.

Other names

SFXN4, also known as sideroflexin 4, is a breast cancer resistance marker 1 protein that plays a crucial role in the regulation of breast cancer development and progression. This protein is a member of the sideroflexin family, which is involved in iron transport and metabolism. BCRM1 is one of the most well-known and extensively studied cancer resistance markers, and SFXN4 has been found to be a critical factor in the resistance of breast cancer cells to chemotherapy. Understanding the function and regulation of SFXN4 could offer new insights into the mechanisms underlying cancer resistance, and potentially lead to the development of new therapies for the treatment of breast and other forms of cancer.

Source

Rabbit

Specificity

SFXN4 Antibody detects endogenous levels of SFXN4.

Species Reactivity

Human

Application

To ensure accurate results, we recommend diluting the primary antibody to a range of 1:500-1:2000 for Western blotting, and 1:100-1:500 for both immunofluorescence and immunocytochemistry. For ELISA using a peptide, we suggest a dilution range of 1:20000-1:40000 for optimal performance.

Immunogen

A synthesized peptide derived from human SFXN4.

Properties

Concentration

1mg/ml

Purification

By utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. This process effectively removed impurities and resulted in a highly refined end product.

Clonality

Polyclonal Antibody

Stability & Storage

To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is important to avoid exposing the product to multiple freeze/thaw cycles as this can affect its effectiveness and integrity. Therefore, it is recommended to handle the product with care and store it properly to ensure its quality is maintained.

Storage buffer

This product contains rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4. It also contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. Proper storage of this product is important, and it should be kept at a temperature of -20 °C. This product has a shelf life of 12 months from the date it was received. Be sure to adhere to these guidelines to ensure optimum results.

Target

Background

Potential iron transporter.

Celluar localization

Mitochondrion;

UniPort

Q6P4A7