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Rabbit Anti-CHML Polyclonal Antibody#abs134671

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Description

Catalog-specification	Delivery time	USD price
abs134671-100ug	1-2 Weeks	301.0
abs134671-50ug	1-2 Weeks	201.0

Overview
catalog	abs134671
Other names	Protein CHM, also known as Chml or Choroideraemia like protein, is a significant component in the regulation of cellular processes. It shares a close resemblance to Choroideraemia-like protein and is also referred to as Choroideremia like (Rab escort protein 2) or Choroideremia like protein. Another name for this protein is Rab escort protein 2, which plays a role in the geranylgeranyltransferase process of Rab proteins. It is commonly denoted as RAE2_HUMAN, REP 2, and REP-2. REP2 is essential for the proper functioning of various molecular mechanisms. Through its versatile functions, CHM contributes significantly to cellular dynamics and is crucial for maintaining physiological balance.
Source	Rabbit
Specificity	Endogenous levels of total CHML can be detected by the CHML Antibody. An alternative speech pattern would be: The CHML Antibody is capable of identifying the overall CHML levels that occur naturally within an organism.
Species Reactivity	Human;Mouse
Antigen	CHML
Application	Please note that the rephrased content provided below is generated using a language model, and it may differ significantly from the original text. The suggested dilution ranges for WB are 1:500 to 1:1000, for IHC are 1:50 to 1:200, for IF/ICC are 1:100 to 1:500, and for ELISA (peptide) are 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	85 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store at -20 °C for a year while avoiding repeated freeze/thaw cycles. To ensure the preservation of the product, please refrain from subjecting it to temperature fluctuations.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline, pH 7.4, with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at -20 °C and it can remain stable for 12 months from the date of receipt.
Target
Background	Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Celluar localization	Cytosol;Nucleus;
UniPort	P26374