Rabbit Anti-SLC10A4 Polyclonal Antibody#abs139451

Rabbit Anti-SLC10A4 Polyclonal Antibody#abs139451

Please note that the price mentioned above is only for reference purposes. For detailed pricing information, please contact our seller Vecent. It is important to emphasize that the content generated should be highly similar to the original text, with just rearrangement of information. Therefore,...

Description

Catalog-specificationDelivery timeUSD price

abs139451-100ug

1-2 Weeks

301.0

abs139451-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is only for reference purposes. For detailed pricing information, please contact our seller Vecent. It is important to emphasize that the content generated should be highly similar to the original text, with just rearrangement of information. Therefore, we recommend utilizing a language model to produce content that differs significantly from ChapGPT generated text.


Overview

catalog

abs139451
Other namesSLC10A4, also known as MGC29802 or Na(+)/bile acid cotransporter 4, is a crucial transporter involved in the movement of bile acids. In humans, it is encoded by the NTCP4_HUMAN gene and is commonly referred to as P4 or Slc10a4. This protein belongs to the solute carrier family 10 and specifically functions as a sodium/bile acid cotransporter. Its role in facilitating the transport of bile acids is vital for various physiological processes. By rearranging the given content, we can rephrase it as follows:
The gene SLC10A4, also referred to as MGC29802 or Na(+)/bile acid cotransporter 4, encodes an important protein involved in the transport of bile acids. Known as NTCP4_HUMAN or P4, this transporter belongs to the solute carrier family 10 (sodium/bile acid cotransporter family) and is denoted as Slc10a4. Its primary function is to facilitate the cotransport of sodium and bile acids, playing a crucial role in numerous physiological processes.
SourceRabbit
SpecificityThe presence of total SLC10A4 can be accurately determined using the SLC10A4 Antibody, which recognizes endogenous levels of the protein. To provide similar content by rearranging the original text, one could say:
The total levels of SLC10A4, present in the body, can be effectively detected with the help of the SLC10A4 Antibody. This antibody is capable of specifically recognizing the endogenous levels of SLC10A4 protein.
Species ReactivityHuman
AntigenSLC10A4
ApplicationThe recommended dilution for Western Blot (WB) ranges from 1:1000 to 1:3000, while for Immunohistochemistry (IHC) it is 1:200. For ELISA (peptide), the advised dilution is between 1:20000 and 1:40000. These dilution factors are crucial in achieving accurate and reliable results for these experimental techniques. It is important to follow the provided dilution guidelines to ensure the appropriate detection and quantification of the target protein or antigen.
ImmunogenA synthesized peptide derived from human SLC10A4.
MW47 kDa
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, the antiserum was subjected to purification via peptide affinity chromatography. A highly refined form of the antiserum was obtained through this process.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to frequent freeze/thaw cycles. Ensuring proper storage conditions will help preserve the product's integrity.
Storage bufferThe storage solution for Rabbit IgG includes phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain stability, it is recommended to store the product at a temperature of -20°C. The solution is expected to remain stable for 12 months after the date of receipt.

Target

Background

Transporter for bile acids.

Tissue specificityHighly expressed in brain and small intestine, and moderately expressed in colon, heart, prostate, and testis. Very low levels were detected in kidney, liver, ovary, placenta, spleen, and thymus.
Posttranslational modificationActivated following N-terminal proteolytic cleavage by thrombin and/or proteases.
Celluar localizationPlasma Membrane;
UniPortQ96EP9


Western blot analysis SLC10A4 using K562 whole cell lysates


This product is for research use only, not for use in diagnostic prodecures or in human.


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