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Rabbit Anti-MYO1A Polyclonal Antibody#abs139170

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Description

Catalog-specification	Delivery time	USD price
abs139170-100ug	1-2 Weeks	301.0
abs139170-50ug	1-2 Weeks	201.0

Overview
catalog	abs139170
Other names	Myosin I heavy chain, also known as Brush border myosin I or BBM-I, is a protein encoded by the MYO1A gene. It is a type of myosin that plays a role in various cellular processes such as cell migration, cytokinesis, and endocytosis. MYHL, MIHC, and BBMI are other names for this protein. Mutations in the MYO1A gene have been associated with DFNA48, a genetic disorder characterized by progressive hearing loss. Myosin-IA is another alternative name for this protein, which serves as a heavy polypeptide like (100kD). Research on BBM-I protein has revealed the vital mechanisms, functions, and regulatory properties of myosin I in cells. Overall, this protein is an essential component of microvilli and plays a critical role in the proper functioning of the epithelial cell membrane. So research in this field is vital for the discovery of new treatments for various cellular disorders related to myosin I heavy chain.
Source	Rabbit
Specificity	The total level of endogenous MYO1A can be detected by using the MYO1A antibody. This antibody is capable of identifying all forms of MYO1A present naturally within the organism.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Sheep;Horse;Bovine
Antigen	MYO1A
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human MYO1A.
MW	118kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we employed peptide affinity chromatography to purify the antiserum. This process enabled the removal of any contaminants and ensured a high level of purity in the final product.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to store it at a temperature of -20 °C for one year. It is important to avoid subjecting the product to repeated freezing and thawing cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be kept in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store it at -20 °C. The stability of the IgG is guaranteed for a period of 12 months from the date of receipt. Please note that this rearranged content is generated based on the original information provided and not in the manner that ChapGPT generates content.
Target
Background	Involved in directing the movement of organelles along actin filaments.
Celluar localization	Cytoskeleton;Plasma Membrane;
UniPort	Q9UBC5