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Rabbit Anti-CHD6 Polyclonal Antibody#abs138902

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Description

Catalog-specification	Delivery time	USD price
abs138902-100ug	1-2 Weeks	301.0
abs138902-50ug	1-2 Weeks	201.0

Overview
catalog	abs138902
Other names	CHD6 is an ATP-dependent helicase that plays an important role in DNA binding and unwinding. It is also known as ATP-dependent helicase CHD6 or CHD-6. Another name for CHD6 is CHD5. The human protein CHD6, encoded by the CHD6 gene, is also referred to as CHD6_HUMAN. It belongs to the chromodomain helicase DNA binding protein family and specifically acts as a chromodomain-helicase-DNA-binding protein 6. The protein contains both a helicase C-terminal domain and an SNF2 N-terminal domain, which are essential for its function. In scientific literature, CHD6 is sometimes denoted as KIAA1335 or RP4-620E11.2. It is also associated with the radiation-induced gene B protein or RIGB, which is believed to be induced by radiation exposure.
Source	Rabbit
Specificity	The total CHD6 levels are detected by the CHD6 Antibody, which is capable of detecting the endogenous levels of CHD6. Let me rearrange the provided information to generate a highly similar content: "Detection of total CHD6 is possible with the CHD6 Antibody as it is designed to specifically identify the endogenous levels of CHD6."
Species Reactivity	Human;Mouse
Antigen	CHD6
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CHD6.
MW	305kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography purification. To achieve this, the antiserum was passed through a resin column that was designed to isolate specific peptides. After passing through the column, the antiserum was able to be collected as a highly purified product. This process allows for the isolation of target antibodies, providing researchers with a highly specific tool for their experiments.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is best to store it at a temperature of -20 °C for up to one year. It is important to avoid exposing the product to repeated freeze/thaw cycles as this can have a negative impact on its quality. It is recommended to follow these storage instructions to maintain the integrity of the product.
Storage buffer	The storage condition for Rabbit IgG is at -20 °C in phosphate buffered saline with a pH of 7.4. The solution contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the product is guaranteed for 12 months from the date of receipt.
Target
Background	DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin (PubMed:28533432). Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2.
Tissue specificity	Widely expressed.
Celluar localization	Nucleus;
UniPort	Q8TD26