Rabbit Anti-Cdx2 Polyclonal Antibody#abs131150

abs131124-50ug

1-2 Weeks

201

abs131124-100ug

1-2 Weeks

301

Description

Playing a crucial role in controlling the transcriptional activities of various genes that are expressed in the intestinal epithelium, this protein is vital for a wide range of functions starting from the early differentiation stage to the sustenance of the epithelial lining of both the small and large intestine. Its contribution to the intestinal system cannot be overstated as it ensures that important cellular processes are executed effectively and efficiently.

Other names

CDX2 is a transcription factor belonging to the caudal type homeobox family. It is also referred to as CDX2/AS, CDX3, or Homeobox protein CDX-2. The protein plays a crucial role in regulating gene expression and controlling development processes. CDX2 is involved in various biological functions, including embryogenesis and maintenance of tissue homeostasis. Its presence is significant in multiple cell types and has been extensively studied for its role in intestinal epithelial cell differentiation. The caudal type homeo box 2 protein is also known as Caudal-type homeobox protein 2 or Cdx2. Its various names reflect its importance and diverse functions in cellular processes.

Source

Rabbit

Specificity

Total Cdx2 protein levels are detected by the antibody in the body. The antibody specifically targets the endogenous levels of Cdx2 protein to provide accurate detection.

Application

The recommended dilution for WB is 1:500-1:1000, while for ELISA using peptide, the recommended dilution is 1:20000-1:40000. To ensure accurate results, it is crucial to follow these dilution guidelines closely. By diluting the samples appropriately, you can reduce background noise and improve the signal-to-noise ratio, which is crucial for accurately detecting the target molecule. Therefore, it is vital to pay close attention to the dilution factors and perform the assay with care. Only with precise execution can you achieve reliable and robust results.

SMPYS is a peptide sequence derived from Human Cdx2, specifically around amino acids 12 to 16. To generate a highly similar content, we can rearrange the sequence as follows: SYMPS.

Properties

1mg/ml

Purification

We employed SulfoLink™ Coupling Resin for the purification of the antiserum through peptide affinity chromatography. Let me provide you with a slightly rephrased version of the previous information while ensuring the content remains consistent with the original text.

Clonality

Polyclonal Antibody

To preserve its quality, store the product at -20 °C for a duration of one year. It is crucial to prevent any kind of repeated freeze/thaw cycles.

Storage buffer

pH 7.4, phosphate buffered saline (without Mg2+ and Ca2+), supplied at a concentration of 1.0mg/mL, contains 150mM NaCl. Additionally, it consists of 0.02% sodium azide and 50% glycerol for preservation purposes.

Target

Background

The regulation of multiple genes expressed in the intestinal epithelium is a key role I play. I am involved in various important functions, from the early differentiation of cells to the continuous maintenance of the intestinal lining in both the small and large intestine. My impact extends across a broad range of activities within this biological context. It is my duty to ensure the proper functioning of the intestinal epithelium and facilitate its vital tasks.

Celluar localization

Nucleus;

Q99626