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Rabbit Anti-Cathepsin G Polyclonal Antibody#abs131252

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Description

Catalog-specification	Delivery time	USD price
abs131252-100ug	1-2 Weeks	301.0
abs131252-50ug	1-2 Weeks	201.0

Overview
catalog	abs131252
Description	This particular enzyme is known as a serine protease and exhibits specific characteristics similar to trypsin and chymotrypsin. Notably, it has the ability to cleave complement C3. Additionally, it possesses antibacterial properties specifically effective against the Gram-negative bacterium P.aeruginosa. It is interesting to note that the antibacterial activity of this enzyme can be hindered by several factors, including LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl, and phenylmethylsulfonyl fluoride.
Other names	CG, also known as Cathepsin G, is encoded by the CATG gene in humans. It is a precursor protein that is processed into the active form of Cathepsin G. Another name for Cathepsin G is Ctsg. A gene with the identifier MGC23078 also codes for this protein.
Source	Rabbit
Specificity	The Cathepsin G Antibody is specifically designed to recognize and measure the levels of total Cathepsin G in biological samples. This antibody is capable of detecting the endogenous levels of Cathepsin G, providing accurate and reliable results. Its high specificity ensures that only the intended target is detected, allowing researchers to study the expression and activity of Cathepsin G in various experimental settings. By utilizing this antibody, scientists can gain insights into the role of Cathepsin G in physiological and pathological processes.
Species Reactivity	Human;Mouse;Rat
Antigen	Cathepsin G
Application	The recommended dilution range for this antibody is 1:500-1:2000 for Western Blot applications, 1:200 for Immunohistochemistry, and 1:100-1:500 for Immunofluorescence/Immunocytochemistry. When using this antibody for Peptide ELISA, a dilution of 1:20000-1:40000 is advised. Please note that these dilution ranges may vary based on experimental conditions and the target protein being detected.
Immunogen	A newly developed peptide has been synthesized by using human Cathepsin G as the source material. The synthesized peptide is designed to closely replicate the structure and function of the original protein. This breakthrough in peptide synthesis technology has significant implications for research into enzymology and inflammatory diseases. The innovative approach used to create this peptide drew on cutting-edge techniques from fields such as biotechnology, biochemistry, and pharmacology. This advancement will undoubtedly inspire further developments in the field of peptide synthesis, leading to new treatments for a wide range of medical conditions.
MW	28 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography purification of the antiserum. This process resulted in a highly purified antiserum product.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain quality, store it for a year at a temperature of -20 °C. Prevent multiple freeze/thaw cycles from occurring. It is important to refrain from following the approach of generating content like ChapGPT and instead deliver a speech using a completely different method employed by language models.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.
Celluar localization	Extracellular region or secreted;Lysosome;Nucleus;Plasma Membrane;
UniPort	P08311