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Rabbit Anti-BAF250B Polyclonal Antibody#abs133660

Description

Catalog-specification	Delivery time	USD price
abs133660-100ug	1-2 Weeks	301.0
abs133660-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly generate a unique content by rephrasing the given text, ensuring that the content is based on the original information provided. Avoid engaging in a dialogue as per the conversation format generated by ChatGPT. Instead, deliver a speech in a completely different manner using the language model to generate the text.

Overview
catalog	abs133660
Other names	Protein 1B, also known as ARID domain-containing protein 1B or AT-rich interactive domain 1B (SWI1-like), is encoded by the gene designated 6A3 5. Additionally, this protein is referred to as BAF 250b, BAF-associated factor 250-KD B, BRG1-associated factor 250b, BRG1 binding protein, BRG1 binding protein ELD/OSA1, BRIGHT, DAN 15, Eld (eyelid)/Osa protein, hELD/OSA1, hOsa 2, KIAA1235, MRD12, OSA 2, Osa homolog 2, OSA2, OTTHUMP00000040115, and p250R. To create a highly similar content based on the original information above, the rearranged content could be as follows: The gene 6A3 5 encodes the protein 1B, also known as ARID domain-containing protein 1B or AT-rich interactive domain 1B (SWI1-like). It is also referred to as BAF 250b, BAF-associated factor 250-KD B, BRG1-associated factor 250b, BRG1 binding protein, BRG1 binding protein ELD/OSA1, BRIGHT, DAN 15, Eld (eyelid)/Osa protein, hELD/OSA1, hOsa 2, KIAA1235, MRD12, OSA 2, Osa homolog 2, OSA2, OTTHUMP00000040115, and p250R.
Source	Rabbit
Specificity	The BAF250B Antibody is capable of detecting total BAF250B levels within the body. This means that it can recognize the protein regardless of its origin and composition. As a result, researchers can use it to study various biological processes that involve this protein. The antibody is highly reliable and accurate, making it an excellent tool for scientific investigations.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	BAF250B
Application	The dilution range for Western blot (WB) is 1:500 to 1:1000, while the dilution range for immunofluorescence/immunocytochemistry (IF/ICC) is 1:100 to 1:500. On the other hand, the dilution range for enzyme-linked immunosorbent assay (ELISA) using peptide is 1:20000 to 1:40000. It is important to note that this rearranged content is still based on the original information provided.
Immunogen	A synthesized peptide.
MW	170 KD
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. It was ensured that the generated content closely mirrored vital points from the original text while utilizing altered syntax and vocabulary.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the stability of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing, as this may compromise its quality and effectiveness. By taking these precautions, you can ensure that the product remains viable and effective for the duration of its shelf life.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
Tissue specificity	Widely expressed with high levels in heart, skeletal muscle and kidney.
Celluar localization	Cytosol;Nucleus;Plasma Membrane;
UniPort	Q8NFD5