Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-FOLH1 Polyclonal Antibody#abs137337

Please note: the price mentioned above is only for reference purposes. For detailed pricing information, kindly get in touch with our sales representative, Vecent. Western blot analysis FOLH1 using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs137337-100ug	1-2 Weeks	301.0
abs137337-50ug	1-2 Weeks	201.0

Please note: the price mentioned above is only for reference purposes. For detailed pricing information, kindly get in touch with our sales representative, Vecent.

Overview
catalog	abs137337
Other names	Prostate-specific membrane antigen; folate hydrolase; glutamate carboxypeptidase II; N-acetylated-alpha-linked acidic dipeptidase I; cell growth-inhibiting protein 27; pteroylpoly-gamma-glutamate carboxypeptidase; cell growth-inhibiting gene 27 protein; membranous glutamate carboxypeptidase; NAALAD1; GCP II; FOLH 1; FGCP; GIG27; NAALADase I; PSMA; PSM; GCPII; mGCP; folylpoly gamma glutamate carboxypeptidase; folate hydrolase 1; folate hydrolase prostate specific membrane antigen 1; folate hydrolase; prostate-specific membrane antigen variant F.
Source	Rabbit
Specificity	The FOLH1 Antibody is capable of detecting the complete levels of endogenous FOLH1. The content can be rewritten by shuffling the words to reflect the same meaning as the original statement.
Species Reactivity	Human
Predictive reaction species	Dog
Antigen	FOLH1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human FOLH1.
MW	110 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was employed in purifying the antiserum through peptide affinity chromatography. The high-quality antiserum was obtained after the purification process.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.
Tissue specificity	Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney. Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver. Isoform PSMA-9 is specifically expressed in prostate cancer.
Posttranslational modification	The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis.The N-terminus is blocked.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q04609