Rabbit Anti-Annexin III Polyclonal Antibody#abs131241

abs131241-50ug

1-2 Weeks

201

abs131241-100ug

1-2 Weeks

301

Description

This compound exhibits anti-coagulant effects and acts as an inhibitor of phospholipase A2. Moreover, it is capable of breaking down the cyclic bond present in inositol 1,2-cyclic phosphate, resulting in the formation of inositol 1-phosphate.

Other names

Annexin A3, also known as Annexin-3 or Lipocortin III, is a protein that plays a crucial role in many physiological processes. It is encoded by the ANXA3 gene and its alternative names include Inositol 1,2-cyclic phosphate 2-phosphohydrolase, 35-alpha Calcimedin, PAP III, Placental Anticoagulant Protein III, among others.
Annexin A3 is a member of the annexin family of proteins which are calcium-dependent phospholipid-binding proteins. It binds to membrane phospholipids in a calcium-dependent manner and has been shown to regulate cell growth and differentiation, cell adhesion, membrane organization, and signal transduction.
Moreover, Annexin A3 has been implicated in various physiological and pathological processes including inflammation, apoptosis, cancer, and thrombosis. Studies have shown that it is highly expressed in certain cancer types and may play a role in tumor development and progression.
In conclusion, Annexin A3 is a multifunctional protein that is involved in several important biological processes and has potential clinical significance. Its diverse range of functions make it an interesting target for therapeutic interventions in various diseases.

Source

Rabbit

Specificity

The Annexin III Antibody has the ability to identify Annexin III at its native amounts. The total amount of Annexin III present in a sample can be detected using this antibody.

Predictive reaction species

Xenopus;Rabbit;Sheep;Dog;Bovine

Application

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- ELISA（）1:20000-1:40000
- WB 1:500-1:2000
- IHC 1:50-1:200
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Human Annexin III has been used to synthesize a peptide with high similarity. The peptide was derived from Annexin III through a series of rearrangements and modifications. This synthetic peptide retains the structural and functional properties of the original Annexin III, making it a valuable tool in various biological and medical research applications. It offers a more convenient and controlled experimental system compared to using the entire Annexin III protein. The synthesis process ensures that the resulting peptide closely resembles the original Annexin III, allowing researchers to study its interactions, functions, and potential therapeutic applications.

Properties

1mg/ml

Purification

Using SulfoLink™ Coupling Resin, the antiserum went through peptide affinity chromatography purification. A highly similar content can be generated by rephrasing and rearranging the original text, while keeping the information intact.

Clonality

Polyclonal Antibody

To maintain the quality of the stored items, it is recommended to keep them in a freezer at a temperature of -20 °C for a period of one year. It is important to make sure that the products are not subjected to multiple freeze/thaw cycles as this can adversely affect their integrity.

Storage buffer

This product is Rabbit IgG in a phosphate buffered saline solution with a pH of 7.4. It contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and is stable for a period of 12 months from the date of receipt.

Target

Background

This compound exhibits anti-coagulant properties and acts as an inhibitor of phospholipase A2. Additionally, it has the ability to cleave the cyclic bond found in inositol 1,2-cyclic phosphate, resulting in the formation of inositol 1-phosphate. By rearranging the given information, a similar yet distinct content can be produced.

Celluar localization

P12429