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Rabbit Anti-EMR2 Polyclonal Antibody#abs135177

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Description

Catalog-specification	Delivery time	USD price
abs135177-50ug	1-2 Weeks	201.0
abs135177-100ug	1-2 Weeks	301.0

Overview
catalog	abs135177
Other names	CD 312; CD 312 antigen; CD312; CD312 antigen; Egf like module containing mucin like hormone receptor like 2; Egf like module containing mucin like hormone receptor like sequence 2; EGF like module EMR2; EGF-like module receptor 2; EGF-like module-containing mucin-like hormone receptor-like 2; EMR2; EMR2_HUMAN. Here are some rearranged versions of the given text information: 1. EMR2_HUMAN is also known as CD 312, CD312 antigen, or CD312. It is a receptor that contains an Egf-like module and mucin-like hormone receptor-like sequence 2. 2. The EGF-like module receptor 2, also called CD312 or CD312 antigen, is a receptor that consists of an Egf-like module along with a mucin-like hormone receptor-like sequence 2. 3. CD312 or CD312 antigen, also known as EMR2_HUMAN, is a receptor that contains an Egf-like module and a mucin-like hormone receptor-like sequence 2. 4. The receptor EMR2_HUMAN, also referred to as EGF-like module receptor 2 or CD312 antigen, consists of an Egf-like module and mucin-like hormone receptor-like sequence 2. Please note that the generated content is based on the original text information, but rearranged to provide different variations.
Source	Rabbit
Specificity	The total EMR2 antibody is capable of detecting the endogenous levels of EMR2 protein. In other words, this antibody can accurately identify and measure the amount of EMR2 present within a biological sample.
Species Reactivity	Human
Antigen	EMR2
Application	Here are some alternative ways to express the same information: - When performing Western blotting, dilute your primary antibody at a ratio of 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, use a dilution of 1:100 to 1:500. To conduct an ELISA assay with a peptide antigen, the recommended antibody dilution range is 1:20000 to 1:40000. - To prepare your primary antibody for Western blotting, use a dilution range of 1:500 to 1:1000. For visualization of your target protein in cells or tissue samples via immunofluorescence or immunocytochemistry, dilute your antibody at a ratio of 1:100 to 1:500. In ELISA experiments using a peptide antigen, you should use an antibody dilution of 1:20000 to 1:40000. - Adjust the dilution of your primary antibody according to the application you are using. For Western blotting, dilute the antibody from 1:500 to 1:1000. If you are performing immunofluorescence or immunocytochemistry, use a dilution range of 1:100 to 1:500. The recommended antibody dilution for ELISA assays with a peptide antigen is 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	85 KD
Properties
Concentration	1mg/ml
purification	Through the use of SulfoLink™ Coupling Resin, peptide affinity chromatography was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to keep it stored at a temperature of -20 °C for up to one year. It's important to avoid any repeated freezing and thawing cycles as this can have a negative impact on the stability and effectiveness of the product. So, be sure to store it in a cool and dry place and handle it with care to get the best results.
Storage buffer	This is a description of Rabbit IgG in a phosphate buffered saline solution with a pH of 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. It should be stored at -20 °C and is stable for 12 months after receipt.
Target
Background	Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).
Tissue specificity	Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested. High expression in mast cells (PubMed:26841242).
Posttranslational modification	Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
Celluar localization	Plasma Membrane;
UniPort	Q9UHX3