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Rabbit Anti-BACH1 Polyclonal Antibody#abs137794

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Description

Catalog-specification	Delivery time	USD price
abs137794-100ug	1-2 Weeks	301.0
abs137794-50ug	1-2 Weeks	201.0

Overview
catalog	abs137794
Other names	BACH1, also known as Basic leucine zipper transcription factor 1 or BTB and CNC homology 1, is a transcription regulator protein that plays a crucial role in gene expression regulation. This protein contains a basic region-leucine zipper motif, which is important for its ability to bind to DNA and modulate transcription. BACH1 is involved in a variety of biological processes, including cell growth, differentiation, and apoptosis, and its dysregulation has been linked to several diseases. This protein is highly conserved across species and is expressed in many tissues, but its function can vary depending on the cellular context. Understanding the role of BACH1 in gene regulation can provide insights into the mechanisms underlying complex cellular processes and may lead to the development of new therapeutic strategies for various diseases.
Source	Rabbit
Specificity	The BACH1 Antibody is capable of detecting total BACH1 levels in the body that occur naturally. You can produce content that is highly similar to the original text by rearranging its key phrases and ideas. However, it is important to emphasize that this content should be based on the information of the original text. It is not recommended to use ChapGPT to generate content in the same way as the original text. Instead, you should use a language model to generate content that is completely distinct from the original text.
Species Reactivity	Human
Predictive reaction species	Rabbit
Antigen	BACH1
Application	The recommended dilutions for Western blot (WB) range from 1:1000 to 1:3000. For immunohistochemistry (IHC), the suggested dilution is 1:200. In the case of immunofluorescence/immunocytochemistry (IF/ICC), the dilution range is 1:100 to 1:500. In ELISA assays using peptides, the optimal dilution is between 1:20000 and 1:40000.
Immunogen	A synthesized peptide derived from human BACH1.
MW	105 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	Please ensure that the storage temperature is maintained at -20 °C for a duration of one year while avoiding any instances of repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
Celluar localization	Nucleus;
UniPort	O14867