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Rabbit Anti-AQP2 Polyclonal Antibody#abs137041

Description

Catalog-specification	Delivery time	USD price
abs137041-100ug	1-2 Weeks	301.0
abs137041-50ug	1-2 Weeks	201.0

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Overview
catalog	abs137041
Other names	ADH; AQP 2; AQP CD; AQP-2; AQP-CD; AQP2; AQP2_HUMAN; AQPCD; Aquaporin 2; Aquaporin CD; Aquaporin-2; Aquaporin-CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel aquaporin 2; Water channel protein for renal collecting duct; WCH CD; WCH-CD; WCHCD; ，。 ADH（Aquaporin 2），AQP-2、AQP2AQPCD，。。AQP-2，ADH。ADH，。，，。ADH。，ADH。
Source	Rabbit
Specificity	The detection of total AQP2 levels within the body is achievable through the utilization of an AQP2 Antibody. This antibody specifically targets the endogenous levels of AQP2 present in the system. By utilizing this antibody, one can effectively detect and analyze the overall expression levels of AQP2.
Species Reactivity	Human;Mouse;Rat
Antigen	AQP2
Application	The recommended dilution for WB is 1:1000 to 3000, while for IHC it is 1:200. For ELISA using peptide, the optimal dilution ranges from 1:20000 to 1:40000. It is important to note that these suggested dilutions may vary depending on the specific application and experimental conditions. Hence, it is crucial to establish the appropriate dilution through titration experiments.
Immunogen	A synthesized peptide derived from human AQP2.
MW	29 kDa.
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. It was able to become highly purified through this process.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. Avoid subjecting the product to repeated cycles of freezing and thawing, as this could compromise its effectiveness. It is important to take the necessary precautions to maintain the integrity of the product and ensure that it remains in optimal condition for use.
Storage buffer	The Rabbit IgG solution is formulated in phosphate buffered saline with a pH of 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at a temperature of -20 °C. The stability of the solution is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Tissue specificity	Expressed in renal collecting tubules.
Posttranslational modification	Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent.
Celluar localization	Endosome;Extracellular region or secreted;Golgi apparatus;Plasma Membrane;
UniPort	P41181