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Rabbit Anti-FGFBP3 Polyclonal Antibody#abs138470

Please note that the price mentioned above is provided for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent. Western blot analysis FGFBP3 using HT29 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or...

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Description

Catalog-specification	Delivery time	USD price
abs138470-100ug	1-2 Weeks	301.0
abs138470-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is provided for your reference only. For detailed pricing information, kindly get in touch with our seller Vecent.

Overview
catalog	abs138470
Other names	Fibroblast growth factor-binding protein 3, also known as FGF-BP3 or FGFBP-3, is encoded by the C10orf13 gene. This protein plays a crucial role in the regulation of fibroblast growth factor (FGF) signaling by binding to FGFs and modulating their activity. FGF-BP3 is involved in various biological processes, including embryonic development, tissue repair, and cancer progression. It has been shown to inhibit FGF-dependent cell proliferation and angiogenesis, suggesting its potential as a therapeutic target for cancer treatment. The functional significance of C10orf13 and its encoded protein FGF-BP3 remains an area of active research and investigation.
Source	Rabbit
Specificity	Total FGFBP3 can be detected using the FGFBP3 Antibody, which is capable of recognizing endogenous levels of the protein.
Species Reactivity	Human
Antigen	FGFBP3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human FGFBP3.
MW	28 kDa
Properties
Concentration	1mg/ml
purification	Purification of the antiserum was carried out using SulfoLink™ Coupling Resin by means of peptide affinity chromatography. The process involved binding the target peptides to the resin which allowed for the selective extraction of the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is advised to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C and kept in phosphate buffered saline with a pH of 7.4. Additionally, it should be maintained in a solution containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product is stable for a period of 12 months from the date of receipt.
Target
Background	A protein known as heparin-binding protein has the ability to bind to FGF2 and prevent its attachment to heparin. This, in turn, likely inhibits the localization of FGF2 on glycosaminoglycans present on the extracellular matrix. As a result, FGF2 is released and can activate FGFR signaling, which causes an increase in vascular permeability.
Celluar localization	Extracellular region or secreted;
UniPort	Q8TAT2