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Phospho-PKC Beta (Ser660) Rabbit Polyclonal Antibody#abs139857

Description

Catalog-specification	Delivery time	USD price
abs139857-100ug	1-2 Weeks	301.0
abs139857-50ug	1-2 Weeks	201.0

Please note that the price provided above is only for reference purposes. For detailed pricing information, please get in touch with our seller Vecent. It is important to emphasize that the quoted price may not be final and may vary depending on various factors that might be considered in determining the final price. As such, it is advisable to confirm the pricing details with Vecent, who will be able to provide accurate and up-to-date information.

Overview
catalog	abs139857
Other names	Protein Kinase C (PKC), also known as KPCA_HUMAN and KPCB_HUMAN, is a group of enzymes that play a crucial role in cell signaling and regulating various cellular processes. There are several isoforms of PKC, including PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC gamma, PKC zeta, PKC-A, PKC2, PKCA, PKCB, PKCD, PKCE, PKCG, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCZ, and more. PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC gamma, and PKC zeta are all different forms of Protein Kinase C alpha. PKC-A and PKC2 are other names or aliases for PKC alpha. PKCA, PKCB, PKCD, PKCE, PKCG, and PRKCA are other variants or forms of Protein Kinase C alpha. PRKCB I, PRKCB II, PRKCB1, PRKCB2, and Protein Kinase C beta 1 are different names or isoforms of Protein Kinase C beta, while PKC-B is another alias for PKC beta. These protein kinase C isoforms are involved in various signaling pathways and have distinct functions within cells. They regulate processes such as cell growth, differentiation, apoptosis, and gene expression. The different forms of PKC have different tissue distribution and subcellular localization, allowing them to respond to specific signals and activate specific downstream pathways. Overall, Protein Kinase C plays a vital role in cellular processes and is an important target for therapeutic interventions in various diseases, including cancer, cardiovascular disorders, and neurological conditions.
Source	Rabbit
Specificity	The Antibody for PKC β (Phospho-Ser660) is designed to identify the levels of phosphorylated Ser660 in endogenous PKC β. It does not detect non-phosphorylated PKC β.
Species Reactivity	Human;Mouse
Antigen	PKC β
Application	The suggested dilution for Western blotting ranges from 1:1000 to 3000. Immunohistochemistry requires a dilution of 1:50 to 1:200. In ELISA assays that use peptides, a dilution of 1:20000 to 1:40000 is recommended. These dilution guidelines have been provided based on the original text information and serve as a reference for performing these experimental techniques.
Immunogen	One possible rearrangement of the given content could be: Phosphorylated Ser660 derived from human PKC β has been used to synthesize a peptide with high similarity to the original protein sequence. This peptide could have potential applications in studying the signaling pathways and functions of PKC β, as well as in drug design for PKC β-related diseases. By harnessing the power of molecular biology and peptide synthesis, researchers are able to create artificial molecules that mimic natural ones and provide insights into the complex workings of the human body.
MW	76894.0
Properties
Concentration	1mg/ml
purification	Sequential chromatography was used to purify the antibody from rabbit serum. The purification process involved affinity purification using phospho- and non-phospho-peptide affinity columns.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the stability and quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this can compromise its integrity. By adhering to these storage guidelines, you can ensure that the product remains effective and safe to use over an extended period of time.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
UniPort	P68404/P05771

Western blot analysis PKC β (Phospho-Ser660) using HepG2 whole cell lysates

This product is for research use only, not for use in diagnostic prodecures or in human.

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