Rabbit Anti-FKBPL Polyclonal Antibody #abs130349

Rabbit Anti-FKBPL Polyclonal Antibody #abs130349

Please note that the price mentioned here is only for your reference. For accurate pricing details, kindly reach out to our sales representative Vecent. Data Examples Western blot analysis on Jurkat cell lysate using FKBPL Antibody This product is for research use only, not for use in diagnostic...

Description

Catalog-specification

Delivery time

USD price

abs130349-50ug

1-2 Weeks

201

abs130349-100ug

1-2 Weeks

301

Please note that the price mentioned here is only for your reference. For accurate pricing details, kindly reach out to our sales representative Vecent.


Overview

Description

The gene FKBPL may play a role in the response to X-ray exposure. It has been found to regulate the stability of the p21 protein by binding to both Hsp90 and p21. FKBPL forms a complex with these proteins, known as a ternary complex, along with CDKN1A/p21 and HSP90AB1/Hsp90. This interaction could have important implications for the regulation of cellular growth and division. Overall, the role of FKBPL in these processes warrants further investigation.

Other names

FK506 binding protein-like (Fkbpl), also known as FK506-binding protein-like or NG7, is a protein encoded by the FKBPL gene in humans. It is also referred to as WAF 1/CIP1 stabilizing protein 39 or WISP39. Fkbpl plays a crucial role in various cellular processes. Rearranging the information from the original text, we can say that Fkbpl, also known as FK506 binding protein-like or NG7, is encoded by the FKBPL gene in humans. It is a WAF 1/CIP1 stabilizing protein 39 or WISP39 and is associated with key cellular functions.

Source

Rabbit

Specificity

FKBPL Antibody detects endogenous levels of FKBPL.

Species Reactivity

Human;Mouse;Rat

Predictive reaction species

Sheep;Bovine;Rabbit

Application

The recommended dilution for WB is 1:500-1:2000, and for IF/ICC, it is 1:100-1:500. For ELISA using peptide detection, the dilution range is suggested to be 1:20000-1:40000. It is advisable to adhere to these guidelines while conducting experiments to achieve optimal results.

Immunogen

A synthesized peptide derived from human FKBPL.

Properties

Concentration

1mg/ml

Purification

Utilizing SulfoLink™ Coupling Resin, peptide affinity chromatography was used to purify the antiserum. A highly similar content can be generated by rephrasing the information presented in the original statement.

Clonality

Polyclonal Antibody

Stability & Storage

To ensure optimal storage conditions, it is recommended to store the product at -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze and thaw cycles, as this can have a negative impact on its stability and effectiveness. By following these storage guidelines, you can help maximize the quality and shelf-life of the product for optimal use.

Storage buffer

This solution contains Rabbit IgG in a phosphate buffered saline solution with a pH of 7.4. It also contains 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at a temperature of -20°C for maximum stability. This solution is stable for a period of 12 months from the date of receipt. It is important to note that the content of this solution should not be rearranged or altered in any way. Its composition should remain the same for optimal effectiveness.

Target

Background

This factor may play a role in the response to X-ray exposure. It functions by controlling the stability of the p21 protein through its interaction with both Hsp90 and p21.

Tissue specificity

This gene is widely expressed throughout the body, with particularly enhanced levels in the testis.

Celluar localization

Cytosol;

UniPort

Q9UIM3


Data Examples

15

Western blot analysis on Jurkat cell lysate using FKBPL Antibody


This product is for research use only, not for use in diagnostic prodecures or in human.


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