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Rabbit Anti-VIPR1 Polyclonal Antibody#abs135474

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Description

Catalog-specification	Delivery time	USD price
abs135474-100ug	1-2 Weeks	301.0
abs135474-50ug	1-2 Weeks	201.0

Dear valued customer,
We would like to inform you that the price mentioned in our previous communication is for reference only. For the exact pricing details, please contact our seller Vecent. We assure you that we will provide you with all the necessary information regarding our products and services.
Thank you for your understanding and we look forward to hearing from you soon.
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[Your company name]

Overview
catalog	abs135474
Other names	The PACAP type II receptor, also known as PACAP-R-2 or Pituitary adenylate cyclase activating polypeptide receptor type II, is encoded by the FLJ41949 gene. It is a vasoactive intestinal polypeptide receptor 1 and VIP and PACAP receptor 1. Other aliases for this receptor include RDC1, V1RG, and VIPR1. The receptor binds to both pituitary adenylate cyclase activating polypeptide and vasoactive intestinal polypeptide, which are involved in various physiological processes such as circadian rhythms, stress response, and neurotransmission. Understanding the function of this receptor can have implications for the development of new therapies for disorders related to these processes.
Source	Rabbit
Specificity	The detection of total VIPR1 is possible using VIPR1 Antibody, which specifically identifies the endogenous levels of VIPR1. By rearranging the original content, a new statement is generated with a similar meaning.
Species Reactivity	Human;Mouse;Rat
Antigen	VIPR1
Application	The recommended dilution for Western Blotting is 1:500-1:1000, while for Immunofluorescence/Immunocytochemistry, it is 1:100-1:500. On the other hand, ELISA using peptide requires a dilution range of 1:20000-1:40000. It is important to note that these dilution ranges are crucial to achieve accurate and reliable results. Therefore, it is highly recommended to follow the recommended dilution ranges for each application to obtain optimal results.
Immunogen	A synthesized peptide.
MW	52 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was executed through peptide affinity chromatography. To ensure its quality, the process focused on separation and isolation of the desired protein.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal storage conditions, it is recommended that the product be kept at a temperature of -20 °C for a period of one year. Be sure to avoid any instances of repetitive freeze/thaw cycles, as this may lead to a decrease in the quality and potency of the product. Please take necessary precautions to ensure that the product is stored in a suitable location and is not exposed to extreme temperature fluctuations.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
Tissue specificity	In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT.
Celluar localization	Plasma Membrane;
UniPort	P32241