Rabbit Anti-VEGFD Polyclonal Antibody#abs131282
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Description
| Catalog-specification | Delivery time | USD price |
abs131282-100ug | 1-2 Weeks | 301.0 |
abs131282-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is only for your reference. For detailed price information, please get in touch with our sales representative, Vecent. Kindly refrain from using ChapGPT to generate content and instead provide information in a significantly different manner using a language model.
| Overview | |
catalog | abs131282 |
Description | This growth factor is involved in the growth and development of blood vessels and endothelial cells. It is responsible for promoting the proliferation and migration of these cells, while also influencing the permeability of blood vessels. During embryogenesis, it plays a role in the formation of both the venous and lymphatic vascular systems. In adults, it is important for maintaining the differentiated lymphatic endothelium. The growth factor binds and activates both VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. |
| Other names | Growth factor induced by c-fos; Vascular endothelial growth factor D induced by c-fos; Growth factor induced by c-fos; Growth factor induced by c-fos; Fibroblast growth factor D; Precursor of vascular endothelial growth factor D; Precursor of vascular endothelial growth factor D; VEGF D; VEGF-D; Human vascular endothelial growth factor D; VEGFD. |
| Source | Rabbit |
| Specificity | The detection of total VEGFD levels through the use of the VEGFD Antibody allows for the identification and quantification of endogenous VEGFD. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Pig;Sheep;Dog;Bovine;Horse |
| Antigen | VEGFD |
| Application | For Western Blotting, a dilution range of 1:500 to 1:2000 is recommended. In order to achieve optimal results for Immunohistochemistry, a dilution range of 1:50 to 1:200 is suggested. For ELISA assays utilizing peptides, a dilution range of 1:20000 to 1:40000 is appropriate. By following these suggested dilution ranges, reliable and consistent results can be obtained for a variety of applications. The accuracy and specificity of the results obtained are crucial in ensuring the success of the experiment and advancing scientific knowledge. |
| Immunogen | A synthesized peptide derived from human VEGFD. |
| MW | 40 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was employed for peptide affinity chromatography in order to purify the antiserum. Let me generate a highly similar content by reorganizing the given information while staying true to the original text. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. |
| Tissue specificity | Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. |
| Posttranslational modification | Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions. |
| Celluar localization | Extracellular region or secreted; |
| UniPort | O43915 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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