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Rabbit Anti-TYMS Polyclonal Antibody#abs137573

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Description

Catalog-specification	Delivery time	USD price
abs137573-100ug	1-2 Weeks	301.0
abs137573-50ug	1-2 Weeks	201.0

Overview
catalog	abs137573
Other names	Tyms thymidylate synthetase, also known as TMP synthase, is an essential enzyme encoded by the TYMS gene in humans. It is classified under the EC number 2.1.1.45 and is also referred to as HsT422, MGC88736, OTTHUMP00000162195, or TYSY_HUMAN. Thymidylate synthase plays a crucial role in DNA synthesis by catalyzing the methylation of deoxyuridine monophosphate (dUMP) to form deoxythymidine monophosphate (dTMP). This reaction is vital for the production of thymine, one of the four nucleotides necessary for DNA replication and repair. Thymidylate synthase is commonly abbreviated as TMS or TS and can be found in various tissues and cell types. The TYMS protein, produced by this gene, is critical for maintaining genomic stability and proper cellular division. By rearranging the provided information, the key details about thymidylate synthase and its associated terms have been presented.
Source	Rabbit
Specificity	The detection of endogenous levels of total TYMS is made possible by the TYMS Antibody. To provide a highly similar content, the rearranged text would be as follows: TYMS Antibody enables the identification of total TYMS at its natural levels within an organism.
Species Reactivity	Human
Antigen	TYMS
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TYMS.
MW	36 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography purification. The resulting purification process yielded a highly refined and purified antiserum sample. This advanced technique has allowed for the isolation and concentration of the desired peptide, ensuring the highest level of quality and specificity possible.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid the product being subjected to repeated freeze and thaw cycles as this can affect its integrity and performance over time. Therefore, it is advisable to take proper precautions when storing and handling the product to ensure its effectiveness and longevity.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in a solution of phosphate buffered saline with a pH of 7.4. The solution should also contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the IgG is guaranteed for a period of 12 months starting from the date of receipt.
Target
Background	Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Celluar localization	Cytosol;Mitochondrion;Nucleus;
UniPort	P04818