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Rabbit Anti-CD3G Polyclonal Antibody#abs137575

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent. Western blot analysis CD3G using HT29 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs137575-100ug	1-2 Weeks	301.0
abs137575-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller, Vecent.

Overview
catalog	abs137575
Other names	The CD3 gamma protein, also known as CD3-GAMMA or CD3g, is an antigen gamma polypeptide that forms part of the TiT3 complex. This molecule plays a crucial role in the T-cell antigen receptor complex by mediating signal transduction and T-cell activation. Its encoding gene, CD3G_HUMAN is expressed in T-cells and is involved in many important biological processes related to immune response and cell signaling. Other names for CD3 gamma include CD3g antigen gamma polypeptide, CD3g molecule gamma (CD3 TCR complex), T-cell receptor T3 gamma chain, and T-cell surface glycoprotein CD3 gamma chain. Its structure consists of extracellular, transmembrane, and cytoplasmic domains, with the extracellular region binding to the T-cell receptor. Despite its essential function in T-cell signaling, CD3 gamma has also been linked to various diseases such as autoimmune disorders and certain types of cancer. However, further research is still needed to fully understand its role in these conditions. In summary, CD3 gamma is a crucial protein in T-cell signaling and immune response, playing a significant role in the T-cell antigen receptor complex. Its functions and potential involvement in various diseases make it a promising target for future therapeutic intervention.
Source	Rabbit
Specificity	The CD3G Antibody can accurately detect total CD3G levels present in the body. This means that it can identify the endogenous levels of CD3G.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	CD3G
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CD3G.
MW	20 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was accomplished through the process of peptide affinity chromatography. To generate a highly similar content, this can be rephrased as: The antiserum underwent peptide affinity chromatography for purification, and SulfoLink™ Coupling Resin was utilized during the procedure.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure durability, it is recommended to keep the product at a temperature of -20 °C for a duration of one year. It is advised to avoid subjecting the item to repeated cycles of freezing and thawing.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	The CD3 complex mediates signal transduction.
Celluar localization	Plasma Membrane;
UniPort	P09693