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Rabbit Anti-GOLM1 Polyclonal Antibody#abs137577

Description

Catalog-specification	Delivery time	USD price
abs137577-100ug	1-2 Weeks	301.0
abs137577-50ug	1-2 Weeks	201.0

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Overview
catalog	abs137577
Other names	Golgi membrane protein 1, also known as GP73 or chromosome 9 open reading frame 155, is a 73 kD protein found in the Golgi complex of human cells. It is encoded by the GOLM1 gene and is also known as GOLM1_HUMAN or Golgi phosphoprotein 2. Another name given to this protein is Golgi protein 73kD. GP73 is a useful biomarker for liver disease and is used in the diagnosis of liver fibrosis. GOLPH 2 or PSEC0257 is another name for this protein and is also used in scientific literature to reference GP73. Understanding the function of this protein in the Golgi complex of human cells is important for understanding liver disease and developing better diagnostic tools.
Source	Rabbit
Specificity	The GOLM1 Antibody is designed to recognize the total amount of the endogenous GOLM1 protein. To produce a similar content, the information from the original text must be rearranged in a different manner while retaining its meaning.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep
Antigen	GOLM1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GOLM1.
MW	80 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20°C for up to a year. Make sure to avoid any instances of repeated freezing and thawing cycles, as this could negatively impact the product's effectiveness. It is important to follow these storage guidelines to ensure that the product maintains its potency and quality over time.
Storage buffer	The Rabbit IgG comes in a phosphate buffered saline solution at a pH of 7.4, with 150mM NaCl, 0.02% sodium azide and 50% glycerol to enhance its stability. It should be stored at a temperature of -20 °C for it to remain potent for up to twelve months from the date of receipt.
Target
Background	Unknown. Cellular response protein to viral infection.
Tissue specificity	Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
Posttranslational modification	Glycosylated.Phosphorylation sites are present in the extracellular medium.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;Golgi apparatus;Plasma Membrane;
UniPort	Q8NBJ4