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Rabbit Anti-Cytochrome C-type Heme Lyase Polyclonal Antibody#abs140619

Rabbit Anti-Cytochrome C-type Heme Lyase Polyclonal Antibody#abs140619

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Description

Catalog-specificationDelivery timeUSD price

abs140619-100ug

1-2 Weeks

301.0

abs140619-50ug

1-2 Weeks

201.0

Please note that the price provided is only for reference purposes. For detailed pricing information, please contact our seller Vecent. It is important to emphasize that the content generated should be based on the original text information but delivered using a highly similar yet different language model to ensure a unique and distinct perspective.


Overview

catalog

abs140619
Other namesCytochrome c heme-lyase, also known as CCHL or CCHL_HUMAN, is an enzyme involved in the synthesis of holocytochrome c. It plays a crucial role in the attachment of heme to cytochrome c, an essential protein in electron transfer reactions. This enzyme, encoded by the DKFZp779I1858 gene, is classified under the EC 4.4.1.17 enzyme class.
The Holocytochrome c synthase (cytochrome c heme lyase) is responsible for the conversion of apo-cytochrome c to its functional form by attaching the heme moiety. It is also referred to as cytochrome c-type heme lyase or holocytochrome c type synthase. In humans, this enzyme is encoded by the HCCS gene.
The holocytochrome c synthase plays a crucial role in maintaining proper mitochondrial function as cytochrome c is involved in oxidative phosphorylation. Mutations in the HCCS gene have been linked to cardioencephalomyopathy and other mitochondrial disorders.
Other synonymous names for this enzyme include MCOPS7, RGD1563855, and RP23-37L2.1. Additionally, it is referred to by various OTTHUMP and OTTMUSP identifiers.
To summarize, CCHL or CCHL_HUMAN, also known as cytochrome c heme-lyase or holocytochrome c synthase, is an enzyme crucial for the synthesis of functional cytochrome c. It is encoded by the HCCS gene and plays an important role in mitochondrial function. The enzyme is associated with various identifiers like MCOPS7, RGD1563855, and RP23-37L2.1, as well as OTTHUMP and OTTMUSP identifiers.
SourceRabbit
SpecificityEndogenous levels of total Cytochrome c-type Heme Lyase can be accurately detected using the Cytochrome c-type Heme Lyase Antibody. The antibody shows high specificity in recognizing and binding to the target protein. This enables researchers to study and analyze the presence of Cytochrome c-type Heme Lyase in various biological samples. By detecting the endogenous levels of Cytochrome c-type Heme Lyase, valuable insights can be gained into its role and function in different cellular processes. The antibody-based detection method ensures reliable and quantitative results, making it a valuable tool for investigating the expression and regulation of Cytochrome c-type Heme Lyase.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesHorse;Dog;
AntigenCytochrome c-type Heme Lyase
ApplicationThe suggested dilutions for WB are 1:500 to 1:1000, for IHC are 1:50 to 1:200, for IF/ICC are 1:100 to 1:500, and for ELISA (peptide) are 1:20000 to 1:40000.
ImmunogenA synthesized peptide.
MW31 KD
Properties

Concentration

1mg/ml

purificationThe SulfoLinkâ„¢ Coupling Resin was utilized to carry out peptide affinity chromatography for the purification of the antiserum. The resulting product was of a high purity level and free from impurities.
ClonalityPolyclonal Antibody
Stability & Storage-20℃，。/。
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Links covalently the heme group to the apoprotein of cytochrome c.

Celluar localizationMitochondrion;
UniPortP53701


Western blot analysis of extracts from HeLa cells, HepG2 cells and COLO cells, using Cytochrome c-type Heme Lyase antibody.


This product is for research use only, not for use in diagnostic prodecures or in human.


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