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Rabbit Anti-TWISTNB Polyclonal Antibody#abs138976

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Description

Catalog-specification	Delivery time	USD price
abs138976-100ug	1-2 Weeks	301.0
abs138976-50ug	1-2 Weeks	201.0

Overview
catalog	abs138976
Other names	The protein known as DNA-directed RNA polymerase I subunit RPA43 is also referred to by several other names, including RPA43_HUMAN, Twist neighbor protein, and Twistnb. This protein plays an important role in the process of gene expression, allowing for the transcription of DNA into RNA. Despite its many names, RPA43 refers to the same essential subunit of RNA polymerase I, which is responsible for producing most of the ribosomal RNA in our cells. Its close association with the TWIST gene has led to its identification as a "Twist neighbor," further highlighting its significance in the regulation of gene expression.
Source	Rabbit
Specificity	The endogenous levels of total TWISTNB can be detected using the TWISTNB Antibody.
Species Reactivity	Human
Antigen	TWISTNB
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TWISTNB.
MW	37 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. Our purification process was successful, resulting in a highly pure antiserum that can be used for various applications. We utilized the resin's ability to covalently attach peptides to the solid phase, facilitating the purification of our target antiserum from a complex mixture. This method of purification is considered both efficient and effective and has been widely used in the industry. Overall, we are confident that our antiserum is of the utmost quality and purity, thanks to our precise purification process.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to multiple cycles of freezing and thawing, as this can have a detrimental effect on its shelf life. Therefore, it is advisable to handle the product with care and follow the recommended storage conditions to ensure its optimal performance.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4. The solution should contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This particular product is stable for a period of 12 months from the date of receipt.
Target
Background	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.
Tissue specificity	Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Celluar localization	Nucleus;
UniPort	Q3B726