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Rabbit Anti-TAOK3 Polyclonal Antibody#abs134985

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to contact our seller, Vecent. Western blot analysis of extracts from K562 cells, using TAOK3 antibody. This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs134985-100ug	1-2 Weeks	301.0
abs134985-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to contact our seller, Vecent.

Overview
catalog	abs134985
Other names	HD CL-09 is a tumor antigen associated with cutaneous T-cell lymphoma (CTCL). It is also known as CTCL-associated antigen HD-CL-09 or cutaneous T-cell lymphoma tumor antigen HD CL-09. Another name for this antigen is dendritic cell-derived protein kinase (DKFZp666H245 or DPK). It is also referred to as FLJ31808, hKFC A, hKFC-A, JIK, JNK/SAPK inhibitory kinase, JNK/SAPK-inhibitory kinase, Jun kinase inhibitory kinase, Jun kinase-inhibitory kinase, KDS, kinase from chicken homolog A, MAP3K18, serine kinase, serine/threonine-protein kinase TAO3, STE20-like kinase, TAO kinase 3, TAOK3, or TAOK3_HUMAN. Additionally, it is sometimes called thousand and one amino acid protein 3.
Source	Rabbit
Specificity	The TAOK3 Antibody is capable of detecting the overall levels of TAOK3 that exist naturally within the body. To convey the same information in a different way, rearrange the original text to read as follows: Detection of endogenous levels of total TAOK3 is made possible with the TAOK3 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	TAOK3
Application	For western blotting, the recommended dilution range is 1:500 to 1:1000. When it comes to immunofluorescence and immunocytochemistry, the optimal dilution range is 1:100 to 1:500. For ELISA using peptide antigens, the suggested dilution is 1:20000 to 1:40000. These guidelines should help ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	110 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
Tissue specificity	Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Posttranslational modification	Autophosphorylated. Phosphorylation at Ser-324 by ATM following DNA damage is required for activation of the p38/MAPK14 stress-activated MAPK cascade. Phosphorylated by LRRK2.
Celluar localization	Plasma Membrane;
UniPort	Q9H2K8