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Rabbit Anti-SPON2 Polyclonal Antibody#abs134984

Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis of extracts from COS7 cells, using SPON2 antibody. This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs134984-100ug	1-2 Weeks	301.0
abs134984-50ug	1-2 Weeks	201.0

Please note that the price provided above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs134984
Other names	Lung cells, both cancerous and non-cancerous, exhibit differential expression of a protein known as DIL-1 or Differentially Expressed in Cancerous and Non-cancerous Lung Cells 1. This protein is also referred to as DIL1, DKFZp686G21139, FLJ16313, FLJ22401, FLJ34460, M spondin, and Mindin. Its functions are not fully understood, but it is believed to be involved in the extracellular matrix as Spondin 2. Antibodies against this protein are available for research purposes. The identification of Spondin 2 and its differential expression in cancerous and non-cancerous lung cells may hold potential for understanding lung cancer progression and developing targeted therapies.
Source	Rabbit
Specificity	The total SPON2 present in the body can be detected using the SPON2 Antibody.
Species Reactivity	Human;Mouse;Rat
Antigen	SPON2
Application	For Western blotting, a recommended dilution range of 1:500 to 1:1000 can be used. When performing immunofluorescence or immunocytochemistry, a dilution range of 1:100 to 1:500 is recommended. For ELISA using peptide antigens, a dilution range of 1:20000 to 1:40000 is recommended. Please note that these dilution ranges may need to be adjusted based on the specific experiment and antibody being used.
Immunogen	A synthesized peptide.
MW	37 KD
Properties
Concentration	1mg/ml
purification	Through the use of SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. This process resulted in the production of a highly purified and concentrated antiserum suitable for use in research applications.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is important to keep it at -20°C and avoid subjecting it to repetitive cycles of freezing and thawing. This storage method is recommended for a duration of one year.
Storage buffer	The rabbit IgG contained in this product is suspended in a solution of phosphate buffered saline with a pH value of 7.4, 150 millimolar concentration of sodium chloride, 0.02% sodium azide and 50% glycerol. It is recommended to store the product at -20°C for optimal stability, and it can be used for up to 12 months from the time of receipt.
Target
Background	Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).
Tissue specificity	Expressed in normal lung tissue but not in lung carcinoma cell lines.
Celluar localization	Extracellular region or secreted;
UniPort	Q9BUD6