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Rabbit Anti-SUCNR1 Polyclonal Antibody#abs131413

Please note that the price provided is only for your reference. For more detailed pricing information, we recommend that you get in touch with our seller, Vecent. Western blot analysis of SUCNR1 expression in HUVEC cells This product is for research use only, not for use in diagnostic prodecures...

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Description

Catalog-specification	Delivery time	USD price
abs131413-50ug	1-2 Weeks	201.0
abs131413-100ug	1-2 Weeks	301.0

Please note that the price provided is only for your reference. For more detailed pricing information, we recommend that you get in touch with our seller, Vecent.

Overview
catalog	abs131413
Description	The succinate receptor serves as the binding site for succinate and is primarily expressed in the kidney. This receptor belongs to the G-protein coupled receptor 1 family and exhibits high sequence similarities to other members of this family. Since this receptor is expressed exclusively in the kidney, it may play a role in mediating the physiological actions of succinate within this particular tissue.
Other names	The G protein coupled receptor 91, also known as GPR 91, is an important purinergic receptor of the P2 family that binds to succinate. It is also called the succinate receptor 1, SUCNR1 or SUCN R1. Additionally, it is sometimes referred to as P2Y purinoceptor 1 or P2Y purinoceptor 1-like due to its similarity with other P2 receptors. The GPR 91 receptor plays a significant role in various physiological processes, such as glucose metabolism, immune response and inflammation. It is expressed in different tissues, including adipose tissue, kidney, and liver. Its activation can trigger intracellular signaling pathways that lead to the release of adrenaline, prostaglandins, and many other factors that mediate various biological effects. In summary, G protein coupled receptor 91 or GPR 91 is a crucial molecule involved in the regulation of various physiological processes. Its diverse expression and activation mechanisms are key features that make it an interesting target for drug discovery and therapeutic interventions.
Source	Rabbit
Specificity	The total SUCNR1 levels can be detected by the SUCNR1 Antibody, which specifically targets the endogenous SUCNR1 protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep;Rabbit;Bovine
Antigen	SUCNR1
Application	。WB 1:500-1:2000，IF/ICC 1:100-1:500，ELISA（）1:20000-1:40000。，。。，。
Immunogen	A synthesized peptide derived from human SUCNR1.
MW	38 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to purification through peptide affinity chromatography. The resulting product is highly pure and can be used effectively for its intended purpose.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles as this can have a negative impact on its quality. Therefore, proper storage conditions should be maintained to preserve the integrity of the product for longer.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Receptor for succinate.
Tissue specificity	Expressed specifically in kidney.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q9BXA5