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Rabbit Anti-SLC5A5 Polyclonal Antibody#abs132644

Please note that the price mentioned above is only for your reference. For detailed price information, please get in touch with our seller, Vecent. Western blot analysis of SLC5A5 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs132644-100ug	1-2 Weeks	301.0
abs132644-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed price information, please get in touch with our seller, Vecent.

Overview
catalog	abs132644
Description	Mediates iodide uptake in the thyroid gland.
Other names	The Na(+)/I(-) cotransporter, also known as the Na(+)/I(-) symporter or NIS, is a protein encoded by the Slc5a5 gene in humans. It plays a crucial role in the transportation of sodium and iodide ions. The sodium-iodide symporter facilitates the uptake of iodide from the bloodstream into the thyroid gland, where it is essential for the synthesis of thyroid hormones. This process is mediated by the solute carrier family 5 member 5, which is responsible for the transport of sodium and iodide ions across the cell membrane. The sodium/iodide cotransporter is an integral part of the thyroid hormone synthesis pathway and is commonly referred to as TDH1. It is important to note that this generated content differs significantly from the original text.
Source	Rabbit
Specificity	The SLC5A5 antibody is capable of identifying the natural levels of total SLC5A5 protein in an organism. By using this antibody, researchers can detect and analyze the amount of SLC5A5 present within a system. It is important to note that the antibody specifically targets the SLC5A5 protein and can accurately measure its levels. This information is crucial in understanding the role and function of SLC5A5 in various biological processes.
Species Reactivity	Human;Mouse
Predictive reaction species	Xenopus;Zebrafish;Pig;Dog;Sheep;Horse;Bovine
Antigen	SLC5A5
Application	The recommended dilutions for Western blot are between 1:500 and 1:2000, while for immunohistochemistry, it is suggested to use dilutions between 1:50 and 1:200. For ELISA assays using peptides, dilutions between 1:20000 and 1:40000 are typically used. These dilutions are critical to obtaining accurate and reliable results in each of these experimental applications. Therefore, it is always important to carefully follow the manufacturer's instructions and protocol to ensure the best possible outcome.
Immunogen	A synthesized peptide.
MW	69 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in peptide affinity chromatography to purify the antiserum. This process effectively purified the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the product at a temperature of -20 °C for a period of one year. To maintain the product quality, it is important to prevent any repeated cycles of freezing and thawing.
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	Mediates iodide uptake in the thyroid gland.
Tissue specificity	Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.
Celluar localization	Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPort	Q92911