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Rabbit Anti-SLC5A2 Polyclonal Antibody#abs134818

Description

Catalog-specification	Delivery time	USD price
abs134818-100ug	1-2 Weeks	301.0
abs134818-50ug	1-2 Weeks	201.0

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Overview
catalog	abs134818
Other names	Sodium glucose cotransporter 2, also known as SGLT 2 or low affinity sodium-glucose cotransporter, belongs to the solute carrier family 5 (sodium glucose cotransporter) member 2. It plays a vital role in the transport of sodium and glucose across cell membranes. The gene responsible for encoding this transporter is SLC5A2. Through its active mechanism, it assists in the absorption of glucose from the renal tubules in the kidneys. This protein is essential for maintaining normal blood glucose levels. Alterations in SGLT 2 expression or function can lead to glucose metabolism disorders. Therefore, understanding the molecular details of this sodium-glucose cotransporter is crucial for developing therapeutic strategies to combat diabetes and related conditions.
Source	Rabbit
Specificity	The endogenous levels of total SLC5A2 can be reliably detected using the SLC5A2 Antibody. This antibody specifically targets and detects the total amount of SLC5A2 present in the sample.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Horse
Antigen	SLC5A2
Application	For Western blotting, the recommended dilution range is 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, a dilution range of 1:100 to 1:500 is suggested. For ELISA using peptide substrates, a dilution range of 1:20000 to 1:40000 is appropriate. These dilution ranges are based on the original text information and are intended to provide optimal results for each application. It is important to select the appropriate dilution range for each experiment to ensure accurate and reliable data analysis.
Immunogen	A synthesized peptide.
MW	73 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was accomplished through peptide affinity chromatography. A highly refined and concentrated form of the antiserum was achieved as a result of this process.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to keep the product at a temperature of -20 °C for a duration of one year. It is advised to refrain from subjecting the product to multiple rounds of freezing and thawing.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P31639